7ykf: Difference between revisions

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-'''Unreleased structure'''
-The entry 7ykf is ON HOLD  until Paper Publication
+==Crystal structure of MAGI2 PDZ0-GK/pEphexin4 complex==
+<StructureSection load='7ykf' size='340' side='right'caption='[[7ykf]], [[Resolution|resolution]] 2.28&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7ykf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YKF FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ykf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ykf OCA], [https://pdbe.org/7ykf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ykf RCSB], [https://www.ebi.ac.uk/pdbsum/7ykf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ykf ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MAGI2_MOUSE MAGI2_MOUSE] Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins (By similarity). Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth (By similarity). May play a role in regulating activin-mediated signaling in neuronal cells (PubMed:10681527). Enhances the ability of PTEN to suppress AKT1 activation (By similarity). Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis (PubMed:24608321).[UniProtKB:O88382][UniProtKB:Q86UL8]<ref>PMID:10681527</ref> <ref>PMID:24608321</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Lin L]]
+[[Category: Zhang M]]
+[[Category: Zhu J]]