5g2u: Difference between revisions
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<StructureSection load='5g2u' size='340' side='right'caption='[[5g2u]], [[Resolution|resolution]] 1.43Å' scene=''> | <StructureSection load='5g2u' size='340' side='right'caption='[[5g2u]], [[Resolution|resolution]] 1.43Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5g2u]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5g2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5G2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5G2U FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.43Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5g2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5g2u OCA], [https://pdbe.org/5g2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5g2u RCSB], [https://www.ebi.ac.uk/pdbsum/5g2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5g2u ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HEXSF_BACTN HEXSF_BACTN] Exosulfatase involved in the degradation of the glycosaminoglycans (GAGs) chondroitin sulfate (CS), dermatan sulfate (DS) and heparan sulfate (HS). 2-O-sulfatase active on unsaturated non-reducing end hexuronate units. Has a slight preference for HS-derived structures (PubMed:25002587). GAG-specific sulfatases play a key role in the persistence of the major human gut symbiont B.thetaiotaomicron in the host gastrointestinal tract (PubMed:25002587).<ref>PMID:25002587</ref> <ref>PMID:25002587</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bacteroides thetaiotaomicron VPI-5482]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Basle | [[Category: Basle A]] | ||
[[Category: Bolam | [[Category: Bolam DN]] | ||
[[Category: Cartmell | [[Category: Cartmell A]] | ||
[[Category: Crouch | [[Category: Crouch LI]] | ||
[[Category: Czjzek | [[Category: Czjzek M]] | ||
[[Category: Firbank | [[Category: Firbank SJ]] | ||
[[Category: Henrissat | [[Category: Henrissat B]] | ||
[[Category: Lowe | [[Category: Lowe EC]] | ||
[[Category: Murray | [[Category: Murray H]] | ||
[[Category: Terrapon | [[Category: Terrapon N]] | ||
[[Category: Thomas | [[Category: Thomas S]] | ||
[[Category: Turnbull | [[Category: Turnbull J]] | ||