5fx8: Difference between revisions
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<StructureSection load='5fx8' size='340' side='right'caption='[[5fx8]], [[Resolution|resolution]] 2.60Å' scene=''> | <StructureSection load='5fx8' size='340' side='right'caption='[[5fx8]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5fx8]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5fx8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gaeumannomyces_avenae Gaeumannomyces avenae] and [https://en.wikipedia.org/wiki/Komagataella_phaffii_CBS_7435 Komagataella phaffii CBS 7435]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FX8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PRD_900017:triacetyl-beta-chitotriose'>PRD_900017</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fx8 OCA], [https://pdbe.org/5fx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fx8 RCSB], [https://www.ebi.ac.uk/pdbsum/5fx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fx8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MNLOX_GAEAV MNLOX_GAEAV] Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids. At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product. It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as final product.<ref>PMID:15629124</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Gaeumannomyces avenae]] | ||
[[Category: Komagataella phaffii]] | [[Category: Komagataella phaffii CBS 7435]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Chen Y]] | |||
[[Category: Chen | [[Category: Engstrom A]] | ||
[[Category: Engstrom | [[Category: Karkehanadi S]] | ||
[[Category: Karkehanadi | [[Category: Oliw EH]] | ||
[[Category: Oliw | [[Category: Wennman A]] | ||
[[Category: Wennman | |||