5eqh: Difference between revisions
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<StructureSection load='5eqh' size='340' side='right'caption='[[5eqh]], [[Resolution|resolution]] 2.99Å' scene=''> | <StructureSection load='5eqh' size='340' side='right'caption='[[5eqh]], [[Resolution|resolution]] 2.99Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5eqh]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5eqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EQH FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5RF:(2~{S})-3-(2-BROMOPHENYL)-2-[2-(4-METHOXYPHENYL)ETHANOYLAMINO]-~{N}-[(1~{S})-1-PHENYLETHYL]PROPANAMIDE'>5RF</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5RF:(2~{S})-3-(2-BROMOPHENYL)-2-[2-(4-METHOXYPHENYL)ETHANOYLAMINO]-~{N}-[(1~{S})-1-PHENYLETHYL]PROPANAMIDE'>5RF</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eqh OCA], [https://pdbe.org/5eqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eqh RCSB], [https://www.ebi.ac.uk/pdbsum/5eqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eqh ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Disease == | == Disease == | ||
[ | [https://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN] Hereditary cryohydrocytosis with reduced stomatin;Paroxysmal exertion-induced dyskinesia;Encephalopathy due to GLUT1 deficiency;Paroxysmal dystonic choreathetosis with episodic ataxia and spasticity;Childhood absence epilepsy;Epilepsy with myoclonic-astatic seizures. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GTR1_HUMAN GTR1_HUMAN] Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bringmann | [[Category: Bringmann P]] | ||
[[Category: Caboni | [[Category: Caboni L]] | ||
[[Category: Finer-Moore | [[Category: Finer-Moore J]] | ||
[[Category: Heisler | [[Category: Heisler I]] | ||
[[Category: Hillig | [[Category: Hillig R]] | ||
[[Category: Kapoor | [[Category: Kapoor K]] | ||
[[Category: Muller | [[Category: Muller T]] | ||
[[Category: Pedersen | [[Category: Pedersen BP]] | ||
[[Category: Siebeneicher | [[Category: Siebeneicher H]] | ||
[[Category: Stroud | [[Category: Stroud RM]] | ||
[[Category: Waight | [[Category: Waight AB]] | ||