Monoclonal Antibodies 3D structures: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky, Joel L. Sussman

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 * Single chain variable fragment (scFv)
-**[[6ehy]], [[6ehx]], [[6ehw]], [[6ehv]], [[5j75]], [[5j74]], [[5c2b]], [[2a9n]], [[2a9m]], [[6tcs]] – hscFv<br />
+**[[2a9m]], [[2a9n]], [[3juy]], [[4buh]], [[4ut7]], [[5c2b]], [[5c6w]], [[5j74]], [[5j75]], [[5wym]], [[6dn0]], [[6dsi]], [[6ehv]], [[6ehw]], [[6ehy]], [[6ehx]], [[6ffj]], [[6nou]], [[6qb9]], [[6qf9]], [[6qfc]], [[6tcs]], [[7ah1]] – hscFv<br />
-**[[6tco]], [[6tcr]] – hscFv (mutant)<br />
+**[[6tco]], [[6tcr]], [[7kbm]], [[7kbo]] – hscFv (mutant)<br />
 **[[4kv5]] – hscFv + peptide<br />
-**[[1n4x]], [[1moe]], [[5vf2]], [[5i4f]], [[5b3n]], [[4nko]], [[4nkm]], [[4nkd]], [[4h0i]], [[4h0g]], [[4gqp]], [[3umt]], [[3nn8]] – mscFv<br />
+**[[6qb4]] – hscFv + inhibitor<br />
-**[[4p49]], [[4p48]], [[4ouo]] – cscFv<br />
+**[[6uup]] – cascFv  - camelidae<br />
-**[[5yy4]], [[5yd5]], [[5yd4]], [[5yd3]], [[5fxc]], [[5a2l]], [[5a2j]], [[4h0h]] – mscFv + peptide<br />
+**[[6uy3]] – cascFv  - camelidae + MTX<br />
-**[[6j11]] – mscFv + MERS spike N-terminal<br />
+**[[1n4x]], [[1moe]], [[3nn8]], [[3umt]], [[4gqp]], [[4h0g]], [[4h0i]], [[4nkd]], [[4nkm]], [[4nko]], [[5bn3n]], [[5i4f]], [[5vf2]], [[6p79]], [[6s2i]], [[6tnp]], [[6zqk]], [[7aql]], [[7url]] – mscFv<br />
+**[[6k4z]] – mscFv + antigen<br />
+**[[4h0h]], [[5a2i]], [[5a2j]], [[5a2k]], [[5a2l]], [[5fxc]], [[5owp]], [[5yd3]], [[5yd4]], [[5yd5]], [[5yy4]], [[6frj]], [[6fzr]], [[6tgg]] – mscFv + peptide<br />
+**[[6fzq]] – mscFv + peptide + antigen<br />
+**[[6pil]], [[6pk8]], [[6psc]] – rscFv<br />
+**[[4ouo]], [[4p48]], [[4p49]] – cscFv<br />
+**[[6qf6]] – EcscFv<br />
-*scFv: protein complex
+*scFv protein complex
-**[[6ck9]] – hscFv + hFab + Gp41<br />
-**[[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]], [[4yjz]] – hscFv + hemagglutinin<br />
 **[[5m2j]] – hscFv + TNF<br />
 **[[5jz7]] – hscFv + NGF<br />
 **[[5jym]], [[5jyl]] – hscFv + cadherin<br />
-**[[6j71]] - hscFv + ERBB-2<br />
+**[[3h3b]], [[6j71]] - hscFv + ERBB-2<br />
 **[[7cu5]] - hscFv + PD-1<br />
-**[[6pcu]] - hscFv + rotavirus VP4<br />
+**[[7xw7]] – hscFv thyrotropin receptor – Cryo EM<br />
-**[[7a3o]], [[7a3p]], [[7a3q]], [[7a3t]] – hscFv + dengue protein<br />
+**[[7vdh]], [[7vv5]] – hscFv in MRGPRX2 receptor – Cryo EM<br />
+**[[7vdl]], [[7vv3]] – hscFv in MRGPRX2 receptor + cortistatin – Cryo EM<br />
+**[[7vdm]] – hscFv in MRGPRX2 receptor + protachykinin – Cryo EM<br />
+**[[7vuy]], [[7vuz]] – hscFv in MRGPRX2 receptor + PAMP-12 – Cryo EM<br />
+**[[6ol6]], [[6ol7]] – hscFv + hFab <br />
+**[[6y6c]], [[6yye]] – hscFv + TREM-2 <br />
+**[[6qb3]] – hscFv + MCL-1 <br />
+**[[7vyt]] – hscFv + TIGIT <br />
+**[[6g8r]] – hscFv + SP140 <br />
+**[[8dy1]] – hscFv + IL-17A<br />
+**[[6kn9]] – hscFv + IL-1R<br />
+**[[8cz8]] – hscFv + mesothelin<br />
+**[[7df1]] – hscFv + CD98<br />
 **[[6i07]] - hscFv + EPCAM<br />
 **[[5f3j]] – mscFv + Duffy receptor<br />
 **[[6eqc]], [[5ogi]] – mscFv + hexon protein<br />
 **[[5lxa]] – mscFv + adiponectin receptor<br />
-**[[5kve]] – mscFv + Zika envelop protein<br />
-**[[5kov]] – mscFv + vp90<br />
 **[[3ab0]] – mscFv + BCLA protein<br />
 **[[2znx]], [[1dzb]] – mscFv + lysozyme<br />
 **[[2kh2]] – mscFv + interleukin<br />
 **[[7zwf]] – mscFv + P45/48<br />
-**[[5yy4]], [[5yd5]], [[5yd4]], [[5yd3]], [[5fxc]], [[5a2l]], [[5a2j]], [[4h0h]] – mscFv + peptide<br />
+**[[7jtr]] – mscFv + MBP<br />
+**[[4yqx]] – mscFv + IL-2<br />
+**[[7urv]] – mscFv + CD19<br />
+**[[6sxi]] – mscFv + hFab <br />
+**[[6njl]], [[6njn]], [[7ldd]], [[7lde]] – mscFv in AMPA receptor  – Cryo EM<br />
+**[[7xwo]] – mscFv in neurokinin receptor  – Cryo EM<br />
+**[[6k41]], [[6k42]], [[7w6p]], [[7w7e]] – mscFv + transducin + adrenergic receptor + GI1 – Cryo EM<br />
+**[[6dzt]], [[6e0c]], [[6e0p]], [[7k61]], [[7k78]], [[7vbm]] – mscFv in nucleosome – Cryo EM<br />
+**[[8cxc]] – mscFv + hFab + mesothelin<br />
+**[[6dzw]], [[6dzy]] – mscFv + hFab + serotonin transporter – Cryo EM<br />
+**[[7t6u]] – rascFv + hFab + formyl peptide receptor – Cryo EM<br />
+**[[8jd5]], [[8jd6]] – EcscFv + mGlu receptor + GI1 – Cryo EM<br />
+**[[8sps]], [[8spu]] – EcscFv in nucleosome – Cryo EM<br />
+**[[7sqo]] – syscFv in orexin receptor – Cryo EM<br />
+*scFv viral protein complex
+**[[6ck9]] – hscFv + hFab + Gp41<br />
+**[[5wdu]], [[6mtj]], [[6mtn]], [[6mu6]], [[6mu7]], [[6mu8]], [[6muf]], [[6mug]], [[6nm6]] – hscFv + hFab + Gp160<br />
+**[[6vzi]], [[6w03]] – hscFv + hFab + Gp41 + Gp160<br />
+**[[5d9q]], [[6wix]] – hscFv + hFab + Gp41 + Gp120<br />
+**[[6nnf]], [[6nnj]] – hscFv + hFab + Gp41 + Gp120 + Gp160<br />
+**[[4yjz]], [[5uk2]], [[5uk1]], [[5uk0]], [[5ujz]] – hscFv + hemagglutinin<br />
+**[[7swd]] – hscFv + Ebola protein<br />
+**[[6pcu]] - hscFv + rotavirus VP4<br />
+**[[7qqb]] – hscFv + puumala virus protein<br />
+**[[[7pa6]], [7pa7]], [[7paa]] – hscFv + polyoma virus protein<br />
+**[[4ut9]], [[7a3o]], [[7a3p]], [[7a3q]], [[7a3t]] – hscFv + dengue protein<br />
+**[[7cth]] – hscFv + dengue protein – Cryo EM<br />
+**[[6tou]] – hscFv + rabies protein<br />
+**[[7bem]], [[7cyv]], [[7vmu]], [[8gpy]] – hscFv + SARS spike RBD<br />
+**[[7yue]] – hscFv + SARS spike peptide<br />
+**[[8cxg]] – hscFv + Zika envelop protein – Cryo EM<br />
+**[[7fei]], [[7fej]] – scFv + foot-and-mouth virus protein – bovine – Cryo EM<br />
+**[[5kve]] – mscFv + Zika envelop protein<br />
+**[[5kov]] – mscFv + astrovirus vp90<br />
 **[[6j11]] – mscFv + MERS spike N-terminal<br />
+**[[8dce]] – mscFv + SARS spike RBD<br />
+**[[7t3m]] – mscFv + SARS spike RBD – Cryo EM<br />
 **[[7k93]] – mscFv + dengue protein<br />
+**[[6h3t]], [[6h3u]] – mscFv + schmalenberg virus protein<br />
+**[[7rk1]], [[7rk2]] – mscFv + astrovirus protein<br />
+**[[6lgw]] – mscFv + rabies protein<br />
+**[[6cvk]], [[6cwd]] – rscFv + hepatitis B protein<br />
 }}
 [[Category:Topic Page]]