Mitogen-activated protein kinase 3D structures: Difference between revisions
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**[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br /> | **[[4g6n]], [[4g6o]], [[4gsb]] – hMAPK1 - human<br /> | ||
**[[6d5y]] – hMAPK1 (mutant)<br /> | **[[6d5y]], [[7e73]], [[7e75]] – hMAPK1 (mutant)<br /> | ||
**[[6rfo]] – hMAPK1/MAPK14 peptide<br /> | **[[6rfo]] – hMAPK1/MAPK14 peptide<br /> | ||
**[[3i5z]], [[3i60]], [[3w55]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]], [[4n4s]], [[4o6e]], [[4qp1]], [[4qp2]], [[4qp3]], [[4qp4]], [[4qp6]], [[4qp7]], [[4qp8]], [[4qp9]] [[4qpa]], [[4qta]], [[4qte]], [[4xj0]], [[4xne]], [[4xoy]], [[4xoz]], [[4xp0]], [[4xp2]], [[4xp3]], [[4xrj]], [[4xrl]], [[4zzm]], [[4zzn]], [[4zzo]], [[5bue]], [[5bui]], [[5buj]], [[5bvd]], [[5bve]], [[5bvf]], [[5hd4]], [[5hd7]], [[5k4i]], [[5ke0]], [[5lcj]], [[5lck]], [[5ngu]], [[5nhf]], [[5nhh]], [[5nhj]], [[5nhl]], [[5nho]], [[5nhp]], [[5nhv]], [[5u6i]], [[5wp1]], [[6dmg]], [[6g8x]], [[6g91]], [[6g92]], [[6g93]], [[6g97]], [[6g9a]], [[6g9d]], [[6g9h]], [[6g9j]], [[6g9k]], [[6g9m]], [[6g9n]], [[6dcg]], [[6gjd]], [[6gjb]], [[6ge0]], [[6gdq]], [[6gdm]], [[6g9n]], [[6g54]], [[6nbs]], [[6oph]], [[6opi]], [[6qaw]], [[6qaq]], [[6qal]], [[6qah]], [[6qag]], [[6qa4]], [[6qa3]], [[6qa1]], [[6q7t]], [[6q7s]], [[6q7k]], [[6rq4]], [[7auv]], [[7nqq]], [[7nqw]], [[7nr3]], [[7nr5]], [[7nr8]], [[7nr9]] – hMAPK1+inhibitor - human<br /> | **[[3i5z]], [[3i60]], [[3w55]], [[2ojg]], [[2oji]], [[2ojj]], [[1wzy]], [[1tvo]], [[3sa0]], [[4fux]], [[4fuy]], [[4fv0]], [[4fv1]], [[4fv2]], [[4fv3]], [[4fv4]], [[4fv5]], [[4fv6]], [[4fv7]], [[4fv8]], [[4fv9]], [[4n4s]], [[4o6e]], [[4qp1]], [[4qp2]], [[4qp3]], [[4qp4]], [[4qp6]], [[4qp7]], [[4qp8]], [[4qp9]] [[4qpa]], [[4qta]], [[4qte]], [[4xj0]], [[4xne]], [[4xoy]], [[4xoz]], [[4xp0]], [[4xp2]], [[4xp3]], [[4xrj]], [[4xrl]], [[4zzm]], [[4zzn]], [[4zzo]], [[5bue]], [[5bui]], [[5buj]], [[5bvd]], [[5bve]], [[5bvf]], [[5hd4]], [[5hd7]], [[5k4i]], [[5ke0]], [[5lcj]], [[5lck]], [[5ngu]], [[5nhf]], [[5nhh]], [[5nhj]], [[5nhl]], [[5nho]], [[5nhp]], [[5nhv]], [[5u6i]], [[5wp1]], [[6dmg]], [[6g8x]], [[6g91]], [[6g92]], [[6g93]], [[6g97]], [[6g9a]], [[6g9d]], [[6g9h]], [[6g9j]], [[6g9k]], [[6g9m]], [[6g9n]], [[6dcg]], [[6gjd]], [[6gjb]], [[6ge0]], [[6gdq]], [[6gdm]], [[6g9n]], [[6g54]], [[6nbs]], [[6oph]], [[6opi]], [[6qaw]], [[6qaq]], [[6qal]], [[6qah]], [[6qag]], [[6qa4]], [[6qa3]], [[6qa1]], [[6q7t]], [[6q7s]], [[6q7k]], [[6rq4]], [[7auv]], [[7nqq]], [[7nqw]], [[7nr3]], [[7nr5]], [[7nr8]], [[7nr9]], [[7w5o]], [[7x4u]], [[7xc1]], [[8ao2]], [[8ao3]], [[8ao4]], [[8ao5]], [[8ao6]], [[8ao7]], [[8ao8]], [[8ao9]], [[8aoa]], [[8aob]], [[8aoc]], [[8aod]], [[8aoe]], [[8aof]], [[8aog]], [[8aoh]], [[8aoi]], [[8aoj]] – hMAPK1+inhibitor - human<br /> | ||
**[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br /> | **[[2y9q]] – hMAPK1 + MAP kinase-interacting Ser/Thr protein kinase peptide<br /> | ||
**[[3tei]], [[4h3p]], [[4nif]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br /> | **[[3tei]], [[4h3p]], [[4nif]] – hMAPK1 (mutant) + ribosomal protein S6 kinase α-1<br /> | ||
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**[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br /> | **[[4h3q]] – hMAPK1 + MAP2K 2 peptide<br /> | ||
**[[5ax3]] – hMAPK1 + allosteric inhibitor peptide<br /> | **[[5ax3]] – hMAPK1 + allosteric inhibitor peptide<br /> | ||
**[[7opm]] – hMAPK1 + inhibitor peptide + ORF45<br /> | |||
**[[4n0s]] – hMAPK1 + cafeic acid<br /> | **[[4n0s]] – hMAPK1 + cafeic acid<br /> | ||
**[[4zxt]] – hMAPK1 + catechol<br /> | **[[4zxt]] – hMAPK1 + catechol<br /> | ||
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**[[3o71]] - rMAPK1 + colorectal cancer peptide<br /> | **[[3o71]] - rMAPK1 + colorectal cancer peptide<br /> | ||
**[[2fys]] - rMAPK1 + KIM peptide<br /> | **[[2fys]] - rMAPK1 + KIM peptide<br /> | ||
**[[7ugb]] - rMAPK1 + ISG20 peptide<br /> | |||
**[[4s32]] – rMAPK1 + AMPPNP<br /> | **[[4s32]] – rMAPK1 + AMPPNP<br /> | ||
**[[4s33]], [[4s34]] – rMAPK1 (mutant) + AMPPNP<br /> | **[[4s33]], [[4s34]] – rMAPK1 (mutant) + AMPPNP<br /> | ||
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**[[4ic8]] – hMAPK7<br /> | **[[4ic8]] – hMAPK7<br /> | ||
**[[4b99]], [[4zsg]], [[4zsj]], [[4zsl]], [[5byy]], [[5byz]], [[5o7i]], [[6hkn]], [[6hkm]] – hMAPK7+inhibitor<br /> | **[[4b99]], [[4zsg]], [[4zsj]], [[4zsl]], [[5byy]], [[5byz]], [[5o7i]], [[6hkn]], [[6hkm]], [[7pus]] – hMAPK7+inhibitor<br /> | ||
**[[4ic7]] – hMAPK7+ MAP2K 5<br /> | **[[4ic7]] – hMAPK7+ MAP2K 5<br /> | ||
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**[[3e7o]], [[7cml]] - hMAPK9 (mutant)<br /> | **[[3e7o]], [[7cml]] - hMAPK9 (mutant)<br /> | ||
**[[3npc]] – hMAPK9 (mutant)+inhibitor<br /> | **[[3npc]] – hMAPK9 (mutant)+inhibitor<br /> | ||
**[[7n8t]] – hMAPK9 + AMP<br /> | |||
*MAPK10 or JNK3 | *MAPK10 or JNK3 | ||
**[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[4z9l]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]], [[4kkh]], [[4u79]], [[4whz]], [[4x21]], [[4y46]], [[4y5h]], [[3g9l]], [[3g90]], [[3g9n]], [[2p33]], [[6emh]], [[6ekd]], [[7ksi]], [[7ksj]], [[7ksk]], [[7ore]], [[7orf]], [[7s1n]] – hMAPK10 catalytic domain + inhibitor<br /> | **[[3kvx]], [[3fv8]], [[2waj]], [[3fi2]], [[3fi3]], [[3da6]], [[2zdt]], [[2zdu]], [[3cgf]], [[3cgo]], [[2r9s]], [[2o0u]], [[2o2u]], [[2exc]], [[2b1p]], [[1pmn]], [[4z9l]], [[1pmu]], [[1pmv]], [[3oy1]], [[2ok1]], [[3ttj]], [[3tti]], [[3rtp]], [[3v6r]], [[3v6s]], [[4kkh]], [[4u79]], [[4whz]], [[4x21]], [[4y46]], [[4y5h]], [[3g9l]], [[3g90]], [[3g9n]], [[2p33]], [[6emh]], [[6ekd]], [[7ksi]], [[7ksj]], [[7ksk]], [[7ore]], [[7orf]], [[7s1n]], [[8elc]] – hMAPK10 catalytic domain + inhibitor<br /> | ||
**[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br /> | **[[3ptg]], [[4h39]] - hMAPK10 catalytic domain + JIP1 peptide <br /> | ||
**[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br /> | **[[4h36]] – hMAPK10 catalytic domain + ATF2 peptide<br /> | ||
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**[[2lgc]] – hMAPK14 – NMR<br /> | **[[2lgc]] – hMAPK14 – NMR<br /> | ||
**[[3od6]], [[3ody]], [[3odz]], [[3oef]], [[3p4k]], [[2fsl]], [[2fsm]], [[2fso]], [[2fst]], [[1r3c]], [[4e5a]], [[4geo]] – hMAPK14 (mutant)<br /> | **[[3od6]], [[3ody]], [[3odz]], [[3oef]], [[3p4k]], [[2fsl]], [[2fsm]], [[2fso]], [[2fst]], [[1r3c]], [[4e5a]], [[4geo]] – hMAPK14 (mutant)<br /> | ||
**[[3new]], [[3ocg]], [[3mvl]], [[3mvm]], [[3nnu]], [[3nnv]], [[3nnw]], [[3nnx]], [[3nww]], [[3mpt]], [[3lhj]], [[3huc]], [[3itz]], [[3l8x]], [[3kf7]], [[3fi4]], [[3fkl]], [[3fkn]], [[3fko]], [[3fl4]], [[3fln]], [[3flq]], [[3fls]], [[3flw]], [[3fly]], [[3flz]], [[3fmh]], [[3fmj]], [[3fmk]], [[3fml]], [[3flm]], [[3fln]], [[3fsf]], [[3fsk]], [[3kq7]], [[3iph]], [[3hv4]], [[3hv5]], [[3hv6]], [[3hv7]], [[3k3i]], [[3hec]], [[3heg]], [[3gi3]], [[3hp2]], [[3hp5]], [[3hrb]], [[3ha8]], [[3gfe]], [[3hl7]], [[3hll]], [[3gcu]], [[3fc1]], [[3dt1]], [[3e92]], [[3e93]], [[3d7z]], [[3d83]], [[3ctq]], [[2puu]], [[3bx5]], [[3c5u]], [[2zaz]], [[2zb0]], [[2zb1]], [[2qd9]], [[2ewa]], [[2gfs]], [[2baj]], [[2bak]], [[2bal]], [[2baq]], [[1zyj]], [[1wbn]], [[1wbs]], [[1wbt]], [[1wbv]], [[1wbw]], [[1zz2]], [[1zzl]], [[1yqj]], [[1w7h]], [[1w82]], [[1w83]], [[1w84]], [[1oz1]], [[1ouk]], [[1ouy]], [[1m7q]], [[1kv1]], [[1kv2]], [[1di9]], [[2rg5]], [[2rg6]], [[3bv3]], [[3bv2]], [[3fmm]], [[3fmn]], [[3lfa]], [[3mw1]], [[3pg3]], [[3roc]] ,[[2yis]], [[2yiw]], [[2yix]], [[3qud]], [[3que]], [[3rin]], [[3s3i]], [[3s4q]], [[3u8w]], [[3uvp]], [[3uvq]], [[3uvr]], [[3zs5]], [[3zsg]], [[3zsh]], [[3zsi]], [[3zya]], [[4a9y]], [[4aa0]], [[4aa4]], [[4aa5]], [[4aac]], [[4dli]], [[4dlj]], [[4e5b]], [[4eh2]], [[4eh3]], [[4eh4]], [[4eh5]], [[4eh6]], [[4eh7]], [[4eh8]], [[4eh9]], [[4ehv]], [[4ewq]], [[4f9w]], [[4f9y]], [[4fa2]], [[4kin]], [[4kip]], [[4kiq]], [[4l8m]], [[4r3c]], [[4zth]], [[5lar]], [[5ml5]], [[5omh]], [[5omg]], [[5tbe]], [[5tco]], [[6anl]], [[5xyy]], [[5xyx]], [[5wjj]], [[5n68]], [[5n67]], [[5n66]], [[5n65]], [[5n64]], [[5n63]], [[5mz3]], [[5mty]], [[5mtx]], [[5o8v]], [[5o8u]], [[6sfo]], [[6sfk]], [[6sfj]], [[6sfi]], [[6m9l]], [[6m95]], [[6hwv]], [[6hwu]], [[6hwt]], [[6ohd]], [[6qdz]], [[6qe1]], [[6sfi]], [[6sfj]], [[6sfk]], [[6sfo]], [[6so1]], [[6so2]], [[6so4]], [[6sod]], [[6soi]], [[6sot]], [[6sou]], [[6sov]], [[6sp9]], [[6spl]], [[6zwp]] - hMAPK14+inhibitor<br /> | **[[3new]], [[3ocg]], [[3mvl]], [[3mvm]], [[3nnu]], [[3nnv]], [[3nnw]], [[3nnx]], [[3nww]], [[3mpt]], [[3lhj]], [[3huc]], [[3itz]], [[3l8x]], [[3kf7]], [[3fi4]], [[3fkl]], [[3fkn]], [[3fko]], [[3fl4]], [[3fln]], [[3flq]], [[3fls]], [[3flw]], [[3fly]], [[3flz]], [[3fmh]], [[3fmj]], [[3fmk]], [[3fml]], [[3flm]], [[3fln]], [[3fsf]], [[3fsk]], [[3kq7]], [[3iph]], [[3hv4]], [[3hv5]], [[3hv6]], [[3hv7]], [[3k3i]], [[3hec]], [[3heg]], [[3gi3]], [[3hp2]], [[3hp5]], [[3hrb]], [[3ha8]], [[3gfe]], [[3hl7]], [[3hll]], [[3gcu]], [[3fc1]], [[3dt1]], [[3e92]], [[3e93]], [[3d7z]], [[3d83]], [[3ctq]], [[2puu]], [[3bx5]], [[3c5u]], [[2zaz]], [[2zb0]], [[2zb1]], [[2qd9]], [[2ewa]], [[2gfs]], [[2baj]], [[2bak]], [[2bal]], [[2baq]], [[1zyj]], [[1wbn]], [[1wbs]], [[1wbt]], [[1wbv]], [[1wbw]], [[1zz2]], [[1zzl]], [[1yqj]], [[1w7h]], [[1w82]], [[1w83]], [[1w84]], [[1oz1]], [[1ouk]], [[1ouy]], [[1m7q]], [[1kv1]], [[1kv2]], [[1di9]], [[2rg5]], [[2rg6]], [[3bv3]], [[3bv2]], [[3fmm]], [[3fmn]], [[3lfa]], [[3mw1]], [[3pg3]], [[3roc]] ,[[2yis]], [[2yiw]], [[2yix]], [[3qud]], [[3que]], [[3rin]], [[3s3i]], [[3s4q]], [[3u8w]], [[3uvp]], [[3uvq]], [[3uvr]], [[3zs5]], [[3zsg]], [[3zsh]], [[3zsi]], [[3zya]], [[4a9y]], [[4aa0]], [[4aa4]], [[4aa5]], [[4aac]], [[4dli]], [[4dlj]], [[4e5b]], [[4eh2]], [[4eh3]], [[4eh4]], [[4eh5]], [[4eh6]], [[4eh7]], [[4eh8]], [[4eh9]], [[4ehv]], [[4ewq]], [[4f9w]], [[4f9y]], [[4fa2]], [[4kin]], [[4kip]], [[4kiq]], [[4l8m]], [[4r3c]], [[4zth]], [[5lar]], [[5ml5]], [[5omh]], [[5omg]], [[5tbe]], [[5tco]], [[6anl]], [[5xyy]], [[5xyx]], [[5wjj]], [[5n68]], [[5n67]], [[5n66]], [[5n65]], [[5n64]], [[5n63]], [[5mz3]], [[5mty]], [[5mtx]], [[5o8v]], [[5o8u]], [[6sfo]], [[6sfk]], [[6sfj]], [[6sfi]], [[6m9l]], [[6m95]], [[6hwv]], [[6hwu]], [[6hwt]], [[6ohd]], [[6qdz]], [[6qe1]], [[6sfi]], [[6sfj]], [[6sfk]], [[6sfo]], [[6so1]], [[6so2]], [[6so4]], [[6sod]], [[6soi]], [[6sot]], [[6sou]], [[6sov]], [[6sp9]], [[6spl]], [[6zwp]], [[7z6i]] - hMAPK14+inhibitor<br /> | ||
**[[4e6a]], [[4e6c]], [[4e8a]] - hMAPK14+ lipid<br /> | **[[4e6a]], [[4e6c]], [[4e8a]] - hMAPK14+ lipid<br /> | ||
**[[3o8t]], [[3mpa]], [[3obg]], [[3o8u]], [[3o8p]], [[3obj]], [[3oc1]], [[3hub]], [[3l8s]], [[3hv3]], [[3iw5]], [[3iw6]], [[3iw7]], [[3iw8]], [[3k3j]], [[3gc7]], [[3gcp]], [[3gcq]], [[3gcs]], [[3gcv]], [[3ds6]], [[2i0h]], [[1ove]], [[3lfb]], [[3lfc]], [[3lfd]], [[3lfe]], [[3lff]], [[1bl6]], [[1bl7]], [[1bmk]], [[1a9u]], [[1ian]] - hMAPK14 (mutant)+inhibitor<br /> | **[[3o8t]], [[3mpa]], [[3obg]], [[3o8u]], [[3o8p]], [[3obj]], [[3oc1]], [[3hub]], [[3l8s]], [[3hv3]], [[3iw5]], [[3iw6]], [[3iw7]], [[3iw8]], [[3k3j]], [[3gc7]], [[3gcp]], [[3gcq]], [[3gcs]], [[3gcv]], [[3ds6]], [[2i0h]], [[1ove]], [[3lfb]], [[3lfc]], [[3lfd]], [[3lfe]], [[3lff]], [[1bl6]], [[1bl7]], [[1bmk]], [[1a9u]], [[1ian]], [[5o8v]], [[5o8u]], [[7pvu]] - hMAPK14 (mutant)+inhibitor<br /> | ||
**[[2y8o]] – hMAPK14 (mutant) + dual specificity MAP2K peptide<br /> | **[[8a8m]] – hMAPK14 (mutant) + dual specificity MAP2K – Cryo EM<br /> | ||
*[[2y8o]] – hMAPK14 (mutant) + dual specificity MAP2K peptide<br /> | |||
**[[4ka3]], [[4loo]], [[4lop]], [[4loq]] – hMAPK14 + docking peptide<br /> | **[[4ka3]], [[4loo]], [[4lop]], [[4loq]] – hMAPK14 + docking peptide<br /> | ||
**[[5eta]], [[6zqs]] – hMAPK14 + peptide<br /> | **[[5eta]], [[6zqs]] – hMAPK14 + peptide<br /> | ||
**[[3tg1]] – hMAPK14 + MAPK phosphatase 5<br /> | **[[3tg1]] – hMAPK14 + MAPK phosphatase 5<br /> | ||
**[[5etf]] – hMAPK14 + MAPKK 6<br /> | **[[5etf]] – hMAPK14 + MAPKK 6<br /> | ||
**[[2gtn]], [[2gtm]], [[3p5k]], [[3p78]], [[3p79]], [[3p7a]], [[3p7b]], [[3p7c]], [[6spl]], [[6sp9]], [[6sov]], [[6sou]], [[6sot]], [[6soi]], [[6sod]], [[6so4]], [[6so2]], [[6so1]], [[6y4t]], [[6y4u]], [[6y4v]], [[6y4w]], [[6y4x]], [[6y6v]], [[6yjc]], [[6yk7]], [[6zwr]] - mMAPK14+inhibitor<br /> | **[[2gtn]], [[2gtm]], [[3p5k]], [[3p78]], [[3p79]], [[3p7a]], [[3p7b]], [[3p7c]], [[6spl]], [[6sp9]], [[6sov]], [[6sou]], [[6sot]], [[6soi]], [[6sod]], [[6so4]], [[6so2]], [[6so1]], [[6y4t]], [[6y4u]], [[6y4v]], [[6y4w]], [[6y4x]], [[6y6v]], [[6yjc]], [[6yk7]], [[6zwr]], [[7bdo]], [[7bdq]], [[7be4]], [[7be5]] - mMAPK14+inhibitor<br /> | ||
**[[2ghm]], [[2ghl]], [[1ywr]], [[6y7w]], [[6y7x]], [[6y7y]], [[6y7z]], [[6y80]], [[6y81]], [[6y82]], [[6y85]], [[6y8h]], [[6ycu]], [[6ycw]], [[7bdo]], [[7bdq]], [[7be4]], [[7be5]] - mMAPK14 (mutant)+inhibitor<br /> | **[[2ghm]], [[2ghl]], [[1ywr]], [[6y7w]], [[6y7x]], [[6y7y]], [[6y7z]], [[6y80]], [[6y81]], [[6y82]], [[6y85]], [[6y8h]], [[6ycu]], [[6ycw]], [[7bdo]], [[7bdq]], [[7be4]], [[7be5]] - mMAPK14 (mutant)+inhibitor<br /> | ||
**[[3py3]] - mMAPK14 phosphorylated<br /> | **[[3py3]] - mMAPK14 phosphorylated<br /> | ||