5dx7: Difference between revisions
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==Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylic acid== | ==Crystal structure of Mycobacterium tuberculosis malate synthase in complex with 5-(5-chlorothiophen-2-yl)isoxazole-3-carboxylic acid== | ||
<StructureSection load='5dx7' size='340' side='right' caption='[[5dx7]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='5dx7' size='340' side='right'caption='[[5dx7]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5dx7]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5dx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DX7 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5H6:5-(5-CHLOROTHIOPHEN-2-YL)-1,2-OXAZOLE-3-CARBOXYLIC+ACID'>5H6</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id=' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dx7 OCA], [https://pdbe.org/5dx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dx7 RCSB], [https://www.ebi.ac.uk/pdbsum/5dx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dx7 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MASZ_MYCTU MASZ_MYCTU] Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA (By similarity).[HAMAP-Rule:MF_00641] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5dx7" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5dx7" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Malate synthase 3D structures|Malate synthase 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: Huang | [[Category: Huang H-L]] | ||
[[Category: Sacchettini | [[Category: Sacchettini JC]] | ||