7zt5: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of E8 TCR in complex in human MR1 bound to 3FSA== | |||
<StructureSection load='7zt5' size='340' side='right'caption='[[7zt5]], [[Resolution|resolution]] 2.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZT5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7ZS:3-METHANOYL-2-OXIDANYL-BENZOIC+ACID'>7ZS</scene></td></tr> | ||
[[Category: Karuppiah | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zt5 OCA], [https://pdbe.org/7zt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zt5 RCSB], [https://www.ebi.ac.uk/pdbsum/7zt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zt5 ProSAT]</span></td></tr> | ||
[[Category: Robinson | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Karuppiah V]] | |||
[[Category: Robinson RA]] | |||
Latest revision as of 00:14, 29 June 2023
Structure of E8 TCR in complex in human MR1 bound to 3FSAStructure of E8 TCR in complex in human MR1 bound to 3FSA
Structural highlights
FunctionHMR1_HUMAN Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.[1] References |
| ||||||||||||||||||