5dfn: Difference between revisions
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<StructureSection load='5dfn' size='340' side='right'caption='[[5dfn]], [[Resolution|resolution]] 2.38Å' scene=''> | <StructureSection load='5dfn' size='340' side='right'caption='[[5dfn]], [[Resolution|resolution]] 2.38Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5dfn]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DFN OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5dfn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DFN FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dfn OCA], [https://pdbe.org/5dfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dfn RCSB], [https://www.ebi.ac.uk/pdbsum/5dfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dfn ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TAP45_TETTS TAP45_TETTS] Component of a CST-like subcomplex of the holoenzyme telomerase ribonucleoprotein complex, which stimulates telomerase complementary-strand synthesis (PubMed:26551074). Telomerase is an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:26551074). The CST-like subcomplex (also named 7-4-1) binds telomeric single-stranded DNA and coordinates telomere G-strand and C-strand synthesis (PubMed:26551074).<ref>PMID:26551074</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Cascio | [[Category: Tetrahymena thermophila]] | ||
[[Category: Chan | [[Category: Cascio D]] | ||
[[Category: Feigon | [[Category: Chan H]] | ||
[[Category: Sawaya | [[Category: Feigon J]] | ||
[[Category: Sawaya MR]] | |||