8hmp: Difference between revisions

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-'''Unreleased structure'''
-The entry 8hmp is ON HOLD
+==GPR52 with Gs and c17==
+<StructureSection load='8hmp' size='340' side='right'caption='[[8hmp]], [[Resolution|resolution]] 2.77&Aring;' scene=''>
-Authors: Chen, B., Xu, F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hmp]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HMP FirstGlance]. <br>
-Description: GPR52 with Gs and c17
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EN6:N-(2-hydroxyethyl)-5-(hydroxymethyl)-3-methyl-1-[2-[[3-(trifluoromethyl)phenyl]methyl]-1-benzothiophen-7-yl]pyrazole-4-carboxamide'>EN6</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hmp OCA], [https://pdbe.org/8hmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hmp RCSB], [https://www.ebi.ac.uk/pdbsum/8hmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hmp ProSAT]</span></td></tr>
-[[Category: Xu, F]]
+</table>
-[[Category: Chen, B]]
+== Function ==
+[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Chen B]]
+[[Category: Xu F]]