Glucocorticoids: Difference between revisions
No edit summary |
No edit summary |
||
Line 5: | Line 5: | ||
**<scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | **<scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | ||
**<scene name='96/962959/Binding_site/1'>Budesonide binding site</scene>. Water molecule is shown as red sphere. | **<scene name='96/962959/Binding_site/1'>Budesonide binding site</scene>. Water molecule is shown as red sphere. | ||
**<scene name='97/973067/Binding_site/1'>Mometasone furoate binding site</scene>. | |||
*[[Forkhead box proteins]] (FOX) are transcription factors involved in regulation of gene expression.<ref>PMID:17889656</ref>. '''FOXO1''' activation contributes to '''glucocorticoid'''-induced beta cell death<ref>PMID:23435785</ref>. FOX contain a DNA-binding motif (DBD) of 80-100 amino acids having a winged-helix shape. | *[[Forkhead box proteins]] (FOX) are transcription factors involved in regulation of gene expression.<ref>PMID:17889656</ref>. '''FOXO1''' activation contributes to '''glucocorticoid'''-induced beta cell death<ref>PMID:23435785</ref>. FOX contain a DNA-binding motif (DBD) of 80-100 amino acids having a winged-helix shape. |