6y94: Difference between revisions

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 ==Ca2+-bound Calmodulin mutant N53I==
-<StructureSection load='6y94' size='340' side='right'caption='[[6y94]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+<StructureSection load='6y94' size='340' side='right'caption='[[6y94]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[6y94]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y94 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6Y94 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[6y94]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y94 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y94 FirstGlance]. <br>
 </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CALM1, CALM, CAM, CAM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y94 OCA], [https://pdbe.org/6y94 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y94 RCSB], [https://www.ebi.ac.uk/pdbsum/6y94 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y94 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6y94 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y94 OCA], [http://pdbe.org/6y94 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y94 RCSB], [http://www.ebi.ac.uk/pdbsum/6y94 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y94 ProSAT]</span></td></tr>
 </table>
 == Disease ==
-[[http://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN]] The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of CPVT4.  The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of LQT14.
+[https://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN] The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of CPVT4.  The disease is caused by mutations affecting the gene represented in this entry. Mutations in CALM1 are the cause of LQT14.
 == Function ==
-[[http://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN]] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752). Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696).<ref>PMID:16760425</ref> <ref>PMID:23893133</ref> <ref>PMID:26969752</ref> <ref>PMID:27165696</ref>
+[https://www.uniprot.org/uniprot/CALM1_HUMAN CALM1_HUMAN] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425). Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752). Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696).<ref>PMID:16760425</ref> <ref>PMID:23893133</ref> <ref>PMID:26969752</ref> <ref>PMID:27165696</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 21: / Line 20: @@
 </div>
 <div class="pdbe-citations 6y94" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Brohus, M]]
+[[Category: Brohus M]]
-[[Category: Holt, C]]
+[[Category: Holt C]]
-[[Category: Larsen, K T]]
+[[Category: Larsen KT]]
-[[Category: Lau, K]]
+[[Category: Lau K]]
-[[Category: Nielsen, L H]]
+[[Category: Nielsen LH]]
-[[Category: Overgaard, M T]]
+[[Category: Overgaard MT]]
-[[Category: Petegem, F V]]
+[[Category: Petegem FV]]
-[[Category: Sommer, C]]
+[[Category: Sommer C]]
-[[Category: Sorensen, A B]]
+[[Category: Sorensen AB]]
-[[Category: Wimmer, R]]
+[[Category: Wimmer R]]
-[[Category: Cpvt]]
-[[Category: Metal binding protein]]
-[[Category: Metal-binding]]
-[[Category: Mutant]]
-[[Category: Signaling protein]]