4a53: Difference between revisions
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==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6== | ==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6== | ||
<StructureSection load='4a53' size='340' side='right'caption='[[4a53 | <StructureSection load='4a53' size='340' side='right'caption='[[4a53]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A53 FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a53 OCA], [https://pdbe.org/4a53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a53 RCSB], [https://www.ebi.ac.uk/pdbsum/4a53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a53 ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a53 OCA], [https://pdbe.org/4a53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a53 RCSB], [https://www.ebi.ac.uk/pdbsum/4a53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a53 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/EDC3_SCHPO EDC3_SCHPO] Stimulates decapping of both stable and unstable mRNA during mRNA decay. Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from adopting an inactive conformation.<ref>PMID:22085934</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Braun | [[Category: Schizosaccharomyces pombe]] | ||
[[Category: Fromm | [[Category: Braun JE]] | ||
[[Category: Hoffmann | [[Category: Fromm SA]] | ||
[[Category: Izaurralde | [[Category: Hoffmann NA]] | ||
[[Category: Kamenz | [[Category: Izaurralde E]] | ||
[[Category: Sprangers | [[Category: Kamenz J]] | ||
[[Category: Truffault | [[Category: Sprangers R]] | ||
[[Category: Truffault V]] |