4a53: Difference between revisions

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==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6==
==Structural basis of the Dcp1:Dcp2 mRNA decapping complex activation by Edc3 and Scd6==
<StructureSection load='4a53' size='340' side='right'caption='[[4a53]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='4a53' size='340' side='right'caption='[[4a53]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A53 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4a53]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A53 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A53 FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4a54|4a54]]</div></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a53 OCA], [https://pdbe.org/4a53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a53 RCSB], [https://www.ebi.ac.uk/pdbsum/4a53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a53 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a53 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a53 OCA], [https://pdbe.org/4a53 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a53 RCSB], [https://www.ebi.ac.uk/pdbsum/4a53 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a53 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EDC3_SCHPO EDC3_SCHPO]] Stimulates decapping of both stable and unstable mRNA during mRNA decay. Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from adopting an inactive conformation.<ref>PMID:22085934</ref>
[https://www.uniprot.org/uniprot/EDC3_SCHPO EDC3_SCHPO] Stimulates decapping of both stable and unstable mRNA during mRNA decay. Stimulates decapping presumably by preventing the DCP1-DCP2 decapping complex from adopting an inactive conformation.<ref>PMID:22085934</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cbs 356]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Braun, J E]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Fromm, S A]]
[[Category: Braun JE]]
[[Category: Hoffmann, N A]]
[[Category: Fromm SA]]
[[Category: Izaurralde, E]]
[[Category: Hoffmann NA]]
[[Category: Kamenz, J]]
[[Category: Izaurralde E]]
[[Category: Sprangers, R]]
[[Category: Kamenz J]]
[[Category: Truffault, V]]
[[Category: Sprangers R]]
[[Category: Rna binding protein]]
[[Category: Truffault V]]

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