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==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A== | ==Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A== | ||
<StructureSection load='2krk' size='340' side='right'caption='[[2krk | <StructureSection load='2krk' size='340' side='right'caption='[[2krk]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2krk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRK FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krk OCA], [https://pdbe.org/2krk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krk RCSB], [https://www.ebi.ac.uk/pdbsum/2krk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krk ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Acton | [[Category: Acton TB]] | ||
[[Category: Ciccosanti | [[Category: Ciccosanti C]] | ||
[[Category: Everett | [[Category: Everett JK]] | ||
[[Category: Janjua | [[Category: Janjua J]] | ||
[[Category: Liu | [[Category: Liu G]] | ||
[[Category: Montelione | [[Category: Montelione GT]] | ||
[[Category: Nair R]] | |||
[[Category: Nair | [[Category: Rost B]] | ||
[[Category: Rost | [[Category: Shastry R]] | ||
[[Category: Shastry | [[Category: Xiao R]] | ||
[[Category: Xiao | |||
Revision as of 11:47, 14 June 2023
Solution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102ASolution NMR Structure of 26S protease regulatory subunit 8 from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3102A
Structural highlights
FunctionPRS8_HUMAN The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also |
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