2krf: Difference between revisions

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==NMR solution structure of the DNA binding domain of Competence protein A==
==NMR solution structure of the DNA binding domain of Competence protein A==
<StructureSection load='2krf' size='340' side='right'caption='[[2krf]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2krf' size='340' side='right'caption='[[2krf]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2krf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"vibrio_subtilis"_ehrenberg_1835 "vibrio subtilis" ehrenberg 1835]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2krf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRF FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU31680, comA, comA1, comAA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 "Vibrio subtilis" Ehrenberg 1835])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krf OCA], [https://pdbe.org/2krf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krf RCSB], [https://www.ebi.ac.uk/pdbsum/2krf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2krf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2krf OCA], [https://pdbe.org/2krf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2krf RCSB], [https://www.ebi.ac.uk/pdbsum/2krf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2krf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/CMPA_BACSU CMPA_BACSU]] Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes, including genes of the srfA operon, degQ, rapA, rapC, rapE, rapF, etc. Regulates indirectly, through the regulation of comK transcription, the expression of late competence genes.<ref>PMID:16091051</ref>
[https://www.uniprot.org/uniprot/CMPA_BACSU CMPA_BACSU] Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes, including genes of the srfA operon, degQ, rapA, rapC, rapE, rapF, etc. Regulates indirectly, through the regulation of comK transcription, the expression of late competence genes.<ref>PMID:16091051</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibrio subtilis ehrenberg 1835]]
[[Category: Bacillus subtilis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bobay, B G]]
[[Category: Bobay BG]]
[[Category: Cavanagh, J]]
[[Category: Cavanagh J]]
[[Category: Hobbs, C A]]
[[Category: Hobbs CA]]
[[Category: Perego, M]]
[[Category: Perego M]]
[[Category: Thompson, R J]]
[[Category: Thompson RJ]]
[[Category: Activator]]
[[Category: Competence]]
[[Category: Dna-binding]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Two-component regulatory system]]

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