5c9h: Difference between revisions
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<StructureSection load='5c9h' size='340' side='right'caption='[[5c9h]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='5c9h' size='340' side='right'caption='[[5c9h]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5c9h]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5c9h]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetrahymena_thermophila Tetrahymena thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C9H FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c9h OCA], [https://pdbe.org/5c9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c9h RCSB], [https://www.ebi.ac.uk/pdbsum/5c9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c9h ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TERT_TETTS TERT_TETTS] Catalytic component of telomerase, an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747). TERT is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747).<ref>PMID:10944124</ref> <ref>PMID:15696174</ref> <ref>PMID:16462747</ref> <ref>PMID:17322903</ref> <ref>PMID:20713447</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Telomerase|Telomerase]] | *[[Telomerase 3D structures|Telomerase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Tetrahymena thermophila]] | ||
[[Category: Akiyama BM]] | |||
[[Category: Akiyama | [[Category: Jansson LI]] | ||
[[Category: Jansson | [[Category: Lu C]] | ||
[[Category: Lu | [[Category: Ooms A]] | ||
[[Category: Ooms | [[Category: Rubin SM]] | ||
[[Category: Rubin | [[Category: Stone MD]] | ||
[[Category: Stone | |||