5bzc: Difference between revisions

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<StructureSection load='5bzc' size='340' side='right'caption='[[5bzc]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='5bzc' size='340' side='right'caption='[[5bzc]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bzc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZC FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4WT:4,4-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE'>4WT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4WT:4,4-DIMETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE'>4WT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bzj|5bzj]], [[5bze|5bze]], [[5bzf|5bzf]], [[5bzg|5bzg]], [[5bzh|5bzh]], [[5bzi|5bzi]], [[5bzl|5bzl]], [[5bzm|5bzm]], [[5bzn|5bzn]], [[5bzo|5bzo]], [[5bzq|5bzq]], [[5bzp|5bzp]], [[5bzr|5bzr]], [[5bzs|5bzs]], [[5bzt|5bzt]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzc OCA], [https://pdbe.org/5bzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzc RCSB], [https://www.ebi.ac.uk/pdbsum/5bzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzc ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd44, Ly-24 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzc OCA], [http://pdbe.org/5bzc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bzc RCSB], [http://www.ebi.ac.uk/pdbsum/5bzc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE]] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.  
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Finzel, B C]]
[[Category: Finzel BC]]
[[Category: Liu, L K]]
[[Category: Liu LK]]
[[Category: Link module]]
[[Category: Protein binding]]

Latest revision as of 09:13, 7 June 2023

Crystal structure of the murine CD44 hyaluronan binding domain complex with a small moleculeCrystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule

Structural highlights

5bzc is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CD44_MOUSE Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.

See Also

5bzc, resolution 1.95Å

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