5bnd: Difference between revisions
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==Crystal structure of the C-terminal domain of TagH== | ==Crystal structure of the C-terminal domain of TagH== | ||
<StructureSection load='5bnd' size='340' side='right' caption='[[5bnd]], [[Resolution|resolution]] 2.68Å' scene=''> | <StructureSection load='5bnd' size='340' side='right'caption='[[5bnd]], [[Resolution|resolution]] 2.68Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5bnd]] is a 3 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5bnd]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_epidermidis_RP62A Staphylococcus epidermidis RP62A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BND OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BND FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bnd OCA], [https://pdbe.org/5bnd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bnd RCSB], [https://www.ebi.ac.uk/pdbsum/5bnd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bnd ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q5HN63_STAEQ Q5HN63_STAEQ] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Staphylococcus epidermidis RP62A]] | ||
[[Category: Chen | [[Category: Chen SC]] | ||
[[Category: | [[Category: Chen Y]] | ||
Revision as of 09:00, 7 June 2023
Crystal structure of the C-terminal domain of TagHCrystal structure of the C-terminal domain of TagH
Structural highlights
FunctionPublication Abstract from PubMedThe negatively charged bacterial polysaccharides - wall teichoic acids (WTAs) are synthesized intracellularly and exported by a two-component transporter, TagGH, comprising a transmembrane subunit TagG and an ATPase subunit TagH. We determined the crystal structure of the C-terminal domain of TagH (TagH-C) to investigate its function. The structure shows an N-terminal SH3-like subdomain wrapped by a C-terminal subdomain with an anti-parallel beta-sheet and an outer shell of alpha-helices. A stretch of positively charged surface across the subdomain interface is flanked by two negatively charged regions, suggesting a potential binding site for negatively charged polymers, such as WTAs or acidic peptide chains. This article is protected by copyright. All rights reserved. SH3-Like Motif-Containing C-terminal Domain of Staphylococcal Teichoic Acid Transporter Suggests Possible Function.,Ko TP, Tseng ST, Lai SJ, Chen SC, Guan HH, Yang CS, Chen CJ, Chen Y Proteins. 2016 May 23. doi: 10.1002/prot.25074. PMID:27213893[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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