5aqo: Difference between revisions
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<StructureSection load='5aqo' size='340' side='right'caption='[[5aqo]], [[Resolution|resolution]] 2.12Å' scene=''> | <StructureSection load='5aqo' size='340' side='right'caption='[[5aqo]], [[Resolution|resolution]] 2.12Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5aqo]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQO OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[5aqo]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AQO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AQO FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CWS:6-METHYLQUINAZOLIN-4-AMINE'>CWS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CWS:6-METHYLQUINAZOLIN-4-AMINE'>CWS</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aqo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aqo OCA], [https://pdbe.org/5aqo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aqo RCSB], [https://www.ebi.ac.uk/pdbsum/5aqo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aqo ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/HSP7C_HUMAN HSP7C_HUMAN] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.<ref>PMID:10722728</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Heat Shock | *[[BAG family proteins 3D structures|BAG family proteins 3D structures]] | ||
*[[Heat Shock Protein structures|Heat Shock Protein structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Burke R]] | |||
[[Category: Burke | [[Category: Cheeseman MD]] | ||
[[Category: Cheeseman | [[Category: Collins I]] | ||
[[Category: Collins | [[Category: Dobson SE]] | ||
[[Category: Dobson | [[Category: Jeganathan F]] | ||
[[Category: Jeganathan | [[Category: Jones AM]] | ||
[[Category: Jones | [[Category: Jones K]] | ||
[[Category: Jones | [[Category: Kadi N]] | ||
[[Category: Kadi | [[Category: Lee D]] | ||
[[Category: Lee | [[Category: Liu M]] | ||
[[Category: Liu | [[Category: Matthews TP]] | ||
[[Category: Matthews | [[Category: McAndrew C]] | ||
[[Category: McAndrew | [[Category: Osborne JD]] | ||
[[Category: Richards M]] | |||
[[Category: Osborne | [[Category: Rowlands MG]] | ||
[[Category: Richards | [[Category: Westwood IM]] | ||
[[Category: Rowlands | [[Category: Workman P]] | ||
[[Category: Westwood | [[Category: Yahya N]] | ||
[[Category: Workman | [[Category: Van Montfort RLM]] | ||
[[Category: Yahya | |||
[[Category: | |||