8itf: Difference between revisions
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==Cryo-EM structure of the DMCHA-bound mTAAR9-Gs complex== | |||
<StructureSection load='8itf' size='340' side='right'caption='[[8itf]], [[Resolution|resolution]] 3.46Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8itf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ITF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ITF FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8IA:~{N},~{N}-dimethylcyclohexanamine'>8IA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8itf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8itf OCA], [https://pdbe.org/8itf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8itf RCSB], [https://www.ebi.ac.uk/pdbsum/8itf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8itf ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Lian | [https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Guo LL]] | |||
[[Category: Li Q]] | |||
[[Category: Lian S]] | |||
[[Category: Rong NK]] | |||
[[Category: Sun JP]] | |||
[[Category: Xu YF]] | |||
[[Category: Yang F]] | |||
[[Category: Zhang MH]] |