5aeg: Difference between revisions

<table><tr><td colspan='2'>[[5aeg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AEG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AEG FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B9D:(2R,3R,4R,5S,6R)-6-FLUORANYL-6-(HYDROXYMETHYL)OXANE-2,3,4,5-TETROL'>B9D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aeg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aeg OCA], [https://pdbe.org/5aeg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aeg RCSB], [https://www.ebi.ac.uk/pdbsum/5aeg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aeg ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SQASE_ECOLI SQASE_ECOLI] Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ (PubMed:26878550). Also exhibits some alpha-glucosidase activity against alpha-glucosyl fluoride in vitro, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed (PubMed:15294295).<ref>PMID:15294295</ref> <ref>PMID:26878550</ref>

[[Category: Escherichia coli K-12]]

[[Category: Davies GJ]]

[[Category: Goddard-Borger ED]]

[[Category: Jin Y]]

[[Category: Speciale G]]

[[Category: Williams SJ]]