4zyl: Difference between revisions
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<StructureSection load='4zyl' size='340' side='right'caption='[[4zyl]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4zyl' size='340' side='right'caption='[[4zyl]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zyl]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4zyl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodopseudomonas_palustris_CGA009 Rhodopseudomonas palustris CGA009]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZYL FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zyl OCA], [https://pdbe.org/4zyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zyl RCSB], [https://www.ebi.ac.uk/pdbsum/4zyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zyl ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/Q6N5G1_RHOPA Q6N5G1_RHOPA] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Rhodopseudomonas palustris CGA009]] | ||
[[Category: Moffat | [[Category: Moffat K]] | ||
[[Category: Yang | [[Category: Yang X]] | ||
Revision as of 10:46, 18 May 2023
Crystal structure of response regulator RPA3017 in red light signaling of R. palustrisCrystal structure of response regulator RPA3017 in red light signaling of R. palustris
Structural highlights
FunctionPublication Abstract from PubMedTwo-component signal transduction is the major signaling mechanism that enables bacteria to survive and thrive in complex environmental conditions. The photosynthetic bacterium R. palustris employs two tandem bacteriophytochromes, RpBphP2 and RpBphP3, to perceive red-light signals that regulate the synthesis of light-harvesting complexes under low-light conditions. Both RpBphP2 and RpBphP3 are photosensory histidine kinases coupled to the same response regulator RPA3017. Together, they constitute a two-component system that converts a red-light signal into a biological signal. In this work, the crystal structure of RPA3017 in the unphosphorylated form at 1.9 A resolution is presented. This structure reveals a tightly associated dimer arrangement that is conserved among phytochrome-related response regulators. The conserved active-site architecture provides structural insight into the phosphotransfer reaction between RpBphP2/RpBphP3 and RPA3017. Based on structural comparisons and homology modeling, how specific recognition between RpBphP2/RpBphP3 and RPA3017 is achieved at the molecular level is further explored. Structure of the response regulator RPA3017 involved in red-light signaling in Rhodopseudomonas palustris.,Yang X, Zeng X, Moffat K, Yang X Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1215-22. doi:, 10.1107/S2053230X15014661. Epub 2015 Sep 23. PMID:26457509[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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