4zol: Difference between revisions
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<StructureSection load='4zol' size='340' side='right'caption='[[4zol]], [[Resolution|resolution]] 2.50Å' scene=''> | <StructureSection load='4zol' size='340' side='right'caption='[[4zol]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4zol]] is a 6 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4zol]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus], [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZOL FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=55Q:(2R,4R)-4-{[(2-{(1R,3R)-1-(ACETYLOXY)-4-METHYL-3-[METHYL(N-{[(2S)-1-METHYLPIPERIDIN-2-YL]CARBONYL}-D-ISOLEUCYL)AMINO]PENTYL}-1,3-THIAZOL-4-YL)CARBONYL]AMINO}-2-METHYL-5-PHENYLPENTANOIC+ACID'>55Q</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=55Q:(2R,4R)-4-{[(2-{(1R,3R)-1-(ACETYLOXY)-4-METHYL-3-[METHYL(N-{[(2S)-1-METHYLPIPERIDIN-2-YL]CARBONYL}-D-ISOLEUCYL)AMINO]PENTYL}-1,3-THIAZOL-4-YL)CARBONYL]AMINO}-2-METHYL-5-PHENYLPENTANOIC+ACID'>55Q</scene>, <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zol OCA], [https://pdbe.org/4zol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zol RCSB], [https://www.ebi.ac.uk/pdbsum/4zol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zol ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/TBA1B_PIG TBA1B_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Stathmin|Stathmin]] | *[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | ||
*[[Tubulin|Tubulin]] | *[[Tubulin 3D Structures|Tubulin 3D Structures]] | ||
*[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]] | *[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Gallus gallus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | |||
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
[[Category: Wang | [[Category: Wang Y]] | ||
[[Category: Zhang | [[Category: Zhang R]] | ||