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==Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRE== | |||
<StructureSection load='8igs' size='340' side='right'caption='[[8igs]], [[Resolution|resolution]] 3.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8igs]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IGS FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8igs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8igs OCA], [https://pdbe.org/8igs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8igs RCSB], [https://www.ebi.ac.uk/pdbsum/8igs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8igs ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Feng Y]] | |||
[[Category: Gao B]] | |||
[[Category: Lu Y]] | |||
[[Category: Wen A]] | |||
[[Category: Zhao M]] | |||
Revision as of 10:03, 18 May 2023
Cryo-EM structure of RNAP-promoter open complex at lambda promoter PRECryo-EM structure of RNAP-promoter open complex at lambda promoter PRE
Structural highlights
FunctionRPOA_ECOLI DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059] |
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