8hk5: Difference between revisions

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-'''Unreleased structure'''
-The entry 8hk5 is ON HOLD  until Paper Publication
+==C5aR1-Gi-C5a protein complex==
+<StructureSection load='8hk5' size='340' side='right'caption='[[8hk5]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8hk5]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HK5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HK5 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hk5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hk5 OCA], [https://pdbe.org/8hk5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hk5 RCSB], [https://www.ebi.ac.uk/pdbsum/8hk5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hk5 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Bos taurus]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Rattus norvegicus]]
+[[Category: Liu W]]
+[[Category: Wang Y]]
+[[Category: Xu HE]]
+[[Category: Xu Y]]
+[[Category: Zhuang Y]]