4yol: Difference between revisions

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==Human fibroblast growth factor-1 C16S/A66C/C117A/P134A==
==Human fibroblast growth factor-1 C16S/A66C/C117A/P134A==
<StructureSection load='4yol' size='340' side='right' caption='[[4yol]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
<StructureSection load='4yol' size='340' side='right'caption='[[4yol]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4yol]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YOL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YOL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4yol]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YOL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2afg|2afg]], [[1jqz|1jqz]], [[1rg8|1rg8]], [[4q9g|4q9g]], [[4qal|4qal]], [[3hom|3hom]], [[3fjk|3fjk]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yol OCA], [https://pdbe.org/4yol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yol RCSB], [https://www.ebi.ac.uk/pdbsum/4yol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yol ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FGF1, FGFA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yol OCA], [http://pdbe.org/4yol PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4yol RCSB], [http://www.ebi.ac.uk/pdbsum/4yol PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4yol ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Fibroblast growth factor|Fibroblast growth factor]]
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Blaber, M]]
[[Category: Large Structures]]
[[Category: Xia, X]]
[[Category: Blaber M]]
[[Category: Cysteine-free mutant]]
[[Category: Xia X]]
[[Category: Fgf-1]]
[[Category: Fibroblast growth factor-1]]
[[Category: Intramolecular disulfide]]
[[Category: Protein binding]]

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