4xn1: Difference between revisions

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<StructureSection load='4xn1' size='340' side='right'caption='[[4xn1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4xn1' size='340' side='right'caption='[[4xn1]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4xn1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XN1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XN1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4xn1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XN1 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4xms|4xms]], [[4xmt|4xmt]], [[4xmu|4xmu]], [[4xmv|4xmv]], [[4xmw|4xmw]], [[4xmx|4xmx]], [[4xmz|4xmz]], [[4xn2|4xn2]], [[4xn4|4xn4]], [[4xn5|4xn5]], [[4xn7|4xn7]], [[4xn8|4xn8]], [[4xn9|4xn9]], [[4xna|4xna]], [[4xnb|4xnb]], [[4xnd|4xnd]], [[4xo3|4xo3]], [[4xo4|4xo4]], [[4xo5|4xo5]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xn1 OCA], [https://pdbe.org/4xn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xn1 RCSB], [https://www.ebi.ac.uk/pdbsum/4xn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xn1 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pepN, b0932, JW0915 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Membrane_alanyl_aminopeptidase Membrane alanyl aminopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.11.2 3.4.11.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xn1 OCA], [http://pdbe.org/4xn1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xn1 RCSB], [http://www.ebi.ac.uk/pdbsum/4xn1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xn1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI]] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.  
[https://www.uniprot.org/uniprot/AMPN_ECOLI AMPN_ECOLI] Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Membrane alanyl aminopeptidase]]
[[Category: Addlagatta A]]
[[Category: Addlagatta, A]]
[[Category: Gumpena R]]
[[Category: Gumpena, R]]
[[Category: Hydrolase]]

Revision as of 20:43, 26 April 2023

Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-GlutamateCrystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Glutamate

Structural highlights

4xn1 is a 1 chain structure with sequence from Escherichia coli K-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AMPN_ECOLI Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation.

See Also

4xn1, resolution 2.20Å

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