4xjr: Difference between revisions
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<StructureSection load='4xjr' size='340' side='right'caption='[[4xjr]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='4xjr' size='340' side='right'caption='[[4xjr]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4xjr]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4xjr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_respirovirus_3 Human respirovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XJR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OEL:(6R)-2,6-ANHYDRO-3,4,5-TRIDEOXY-6-[(2S)-2,3-DIHYDROXYPROPANOYL]-3-FLUORO-5-[(2-METHYLPROPANOYL)AMINO]-4-TRIAZA-1,2-DIEN-2-IUM-1-YL-L-GULONIC+ACID'>OEL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OEL:(6R)-2,6-ANHYDRO-3,4,5-TRIDEOXY-6-[(2S)-2,3-DIHYDROXYPROPANOYL]-3-FLUORO-5-[(2-METHYLPROPANOYL)AMINO]-4-TRIAZA-1,2-DIEN-2-IUM-1-YL-L-GULONIC+ACID'>OEL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xjr OCA], [https://pdbe.org/4xjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xjr RCSB], [https://www.ebi.ac.uk/pdbsum/4xjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xjr ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HN_PI3H4 HN_PI3H4] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human respirovirus 3]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Carroux | [[Category: Carroux C]] | ||
[[Category: Chavas | [[Category: Chavas L]] | ||
[[Category: Dirr | [[Category: Dirr L]] | ||
[[Category: El-Deeb | [[Category: El-Deeb I]] | ||
[[Category: Guillon | [[Category: Guillon P]] | ||
[[Category: Itzstein | [[Category: Von Itzstein M]] | ||