7zgo: Difference between revisions
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==Cryo-EM structure of human NKCC1 (TM domain)== | |||
<StructureSection load='7zgo' size='340' side='right'caption='[[7zgo]], [[Resolution|resolution]] 2.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zgo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZGO FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=POV:(2S)-3-(HEXADECANOYLOXY)-2-[(9Z)-OCTADEC-9-ENOYLOXY]PROPYL+2-(TRIMETHYLAMMONIO)ETHYL+PHOSPHATE'>POV</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zgo OCA], [https://pdbe.org/7zgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zgo RCSB], [https://www.ebi.ac.uk/pdbsum/7zgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zgo ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Habeck | [https://www.uniprot.org/uniprot/S12A2_HUMAN S12A2_HUMAN] Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume. | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Lindorff-Larsen | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Fenton R]] | ||
[[Category: | [[Category: Gad H]] | ||
[[Category: | [[Category: Habeck M]] | ||
[[Category: | [[Category: Hartmann R]] | ||
[[Category: | [[Category: Kock Flygaard R]] | ||
[[Category: Lindorff-Larsen K]] | |||
[[Category: Lindtoft Rosenbaek L]] | |||
[[Category: Lykkegaard Karlsen J]] | |||
[[Category: Lyons J]] | |||
[[Category: Neumann C]] | |||
[[Category: Nissen P]] | |||
[[Category: Wang Y]] |