4x22: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:


==Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)==
==Crystal structure of Leptospira Interrogans Triosephosphate Isomerase (LiTIM)==
<StructureSection load='4x22' size='340' side='right' caption='[[4x22]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
<StructureSection load='4x22' size='340' side='right'caption='[[4x22]], [[Resolution|resolution]] 2.08&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4x22]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leptospira_interrogans_serovar_icterohaemorrhagiae_str._rga Leptospira interrogans serovar icterohaemorrhagiae str. rga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X22 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X22 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4x22]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans_serovar_Icterohaemorrhagiae_str._RGA Leptospira interrogans serovar Icterohaemorrhagiae str. RGA]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X22 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X22 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LEP2GSC113_RS0110880 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1291351 Leptospira interrogans serovar Icterohaemorrhagiae str. RGA])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x22 OCA], [https://pdbe.org/4x22 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x22 RCSB], [https://www.ebi.ac.uk/pdbsum/4x22 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x22 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Triose-phosphate_isomerase Triose-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.1 5.3.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x22 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x22 OCA], [http://pdbe.org/4x22 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x22 RCSB], [http://www.ebi.ac.uk/pdbsum/4x22 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x22 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TPIS_LEPIN TPIS_LEPIN] Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).[HAMAP-Rule:MF_00147]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 20:


==See Also==
==See Also==
*[[Triose Phosphate Isomerase|Triose Phosphate Isomerase]]
*[[Triose phosphate isomerase 3D structures|Triose phosphate isomerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Leptospira interrogans serovar icterohaemorrhagiae str. rga]]
[[Category: Large Structures]]
[[Category: Triose-phosphate isomerase]]
[[Category: Leptospira interrogans serovar Icterohaemorrhagiae str. RGA]]
[[Category: Balaram, P]]
[[Category: Balaram P]]
[[Category: Murthy, M R.N]]
[[Category: Murthy MRN]]
[[Category: Pareek, V]]
[[Category: Pareek V]]
[[Category: Beta-alpha barrel]]
[[Category: Isomerase]]
[[Category: Tim barrel]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA