4wxg: Difference between revisions
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<StructureSection load='4wxg' size='340' side='right'caption='[[4wxg]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4wxg' size='340' side='right'caption='[[4wxg]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4wxg]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4wxg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_thermophilus_CNRZ1066 Streptococcus thermophilus CNRZ1066]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WXG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WXG FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2BO:N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-THREONINE'>2BO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2BO:N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-THREONINE'>2BO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wxg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wxg OCA], [https://pdbe.org/4wxg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wxg RCSB], [https://www.ebi.ac.uk/pdbsum/4wxg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wxg ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GLYA_STRT1 GLYA_STRT1] Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Serine hydroxymethyltransferase|Serine hydroxymethyltransferase]] | *[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Streptococcus thermophilus CNRZ1066]] | ||
[[Category: Bujons | [[Category: Bujons J]] | ||
[[Category: Clapes | [[Category: Clapes P]] | ||
[[Category: Hernandez | [[Category: Hernandez K]] | ||
[[Category: Joglar | [[Category: Joglar J]] | ||
[[Category: Parella | [[Category: Parella T]] | ||
[[Category: Petrillo | [[Category: Petrillo G]] | ||
[[Category: Uson | [[Category: Uson I]] | ||
[[Category: Wandtke | [[Category: Wandtke C]] | ||
[[Category: Zelen | [[Category: Zelen I]] | ||