4wj0: Difference between revisions

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<StructureSection load='4wj0' size='340' side='right'caption='[[4wj0]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='4wj0' size='340' side='right'caption='[[4wj0]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4wj0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3pv9 3pv9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WJ0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WJ0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4wj0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3pv9 3pv9]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WJ0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cas1, PH1245 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=70601 Pyrococcus horikoshii])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wj0 OCA], [https://pdbe.org/4wj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wj0 RCSB], [https://www.ebi.ac.uk/pdbsum/4wj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wj0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wj0 OCA], [http://pdbe.org/4wj0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wj0 RCSB], [http://www.ebi.ac.uk/pdbsum/4wj0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wj0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CAS1_PYRHO CAS1_PYRHO]] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.  
[https://www.uniprot.org/uniprot/CAS1_PYRHO CAS1_PYRHO] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.


==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Brown, G]]
[[Category: Brown G]]
[[Category: Petit, P]]
[[Category: Petit P]]
[[Category: Savchenko, A]]
[[Category: Savchenko A]]
[[Category: Yakunin, A F]]
[[Category: Yakunin AF]]
[[Category: Crispr-associated cas1]]
[[Category: Dnase]]
[[Category: Immune system]]
[[Category: Metallonuclease]]
[[Category: Nuclease]]
[[Category: Prok immune system]]

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