4v8m: Difference between revisions

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 <SX load='4v8m' size='340' side='right' viewer='molstar' caption='[[4v8m]], [[Resolution|resolution]] 5.57&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4v8m]] is a 86 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei] and [http://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zeq 3zeq], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zex 3zex], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zey 3zey] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zf7 3zf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V8M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4V8M FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4v8m]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei_TREU927 Trypanosoma brucei brucei TREU927]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zeq 3zeq], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zex 3zex], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zey 3zey] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zf7 3zf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V8M FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4v8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v8m OCA], [http://pdbe.org/4v8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v8m RCSB], [http://www.ebi.ac.uk/pdbsum/4v8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v8m ProSAT]</span></td></tr>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v8m OCA], [https://pdbe.org/4v8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v8m RCSB], [https://www.ebi.ac.uk/pdbsum/4v8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v8m ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/Q383I8_TRYB2 Q383I8_TRYB2]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.[HAMAP-Rule:MF_03015] [[http://www.uniprot.org/uniprot/RL40_TRYBB RL40_TRYBB]] Ubiquitin: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).  60S ribosomal protein L40: component of the 60S subunit of the ribosome. [[http://www.uniprot.org/uniprot/Q386L1_TRYB2 Q386L1_TRYB2]] Binds to the 23S rRNA.[RuleBase:RU000576]
+[https://www.uniprot.org/uniprot/Q38BK6_TRYB2 Q38BK6_TRYB2]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 </SX>
 [[Category: Large Structures]]
-[[Category: Trypanosoma brucei]]
+[[Category: Trypanosoma brucei brucei TREU927]]
-[[Category: Trypanosoma brucei brucei]]
+[[Category: Bajaj C]]
-[[Category: Bajaj, C]]
+[[Category: Buss SN]]
-[[Category: Buss, S N]]
+[[Category: Frank J]]
-[[Category: Frank, J]]
+[[Category: Fu J]]
-[[Category: Fu, J]]
+[[Category: Grassucci RA]]
-[[Category: Georges, A des]]
+[[Category: Hashem Y]]
-[[Category: Grassucci, R A]]
+[[Category: Jobe A]]
-[[Category: Hashem, Y]]
+[[Category: Jossinet F]]
-[[Category: Jobe, A]]
+[[Category: Liao HY]]
-[[Category: Jossinet, F]]
+[[Category: Madison-Antenucci S]]
-[[Category: Liao, H Y]]
+[[Category: Westhof E]]
-[[Category: Madison-Antenucci, S]]
+[[Category: Zhang Q]]
-[[Category: Westhof, E]]
+[[Category: Des Georges A]]
-[[Category: Zhang, Q]]
-[[Category: Eukaryotic]]
-[[Category: Expansion segment]]
-[[Category: Kinetoplastid]]
-[[Category: Ribosome]]