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| <SX load='4v4n' size='340' side='right' viewer='molstar' caption='[[4v4n]], [[Resolution|resolution]] 9.00Å' scene=''> | | <SX load='4v4n' size='340' side='right' viewer='molstar' caption='[[4v4n]], [[Resolution|resolution]] 9.00Å' scene=''> |
| == Structural highlights == | | == Structural highlights == |
| <table><tr><td colspan='2'>[[4v4n]] is a 69 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43067 Atcc 43067] and [http://en.wikipedia.org/wiki/Methanococcus_jannaschii Methanococcus jannaschii]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vvk 1vvk], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3j43 3j43] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3j44 3j44]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V4N OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4V4N FirstGlance]. <br> | | <table><tr><td colspan='2'>[[4v4n]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vvk 1vvk], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3j43 3j43] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3j44 3j44]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V4N FirstGlance]. <br> |
| </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j21|3j21]], [[3j2l|3j2l]], [[3j20|3j20]]</td></tr> | | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4n OCA], [https://pdbe.org/4v4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v4n RCSB], [https://www.ebi.ac.uk/pdbsum/4v4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v4n ProSAT]</span></td></tr> |
| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4v4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v4n OCA], [http://pdbe.org/4v4n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4v4n RCSB], [http://www.ebi.ac.uk/pdbsum/4v4n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4v4n ProSAT]</span></td></tr> | |
| </table> | | </table> |
| == Function ==
| |
| [[http://www.uniprot.org/uniprot/SECG_METJA SECG_METJA]] Subunit of the protein translocation channel SecYEG. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex. [[http://www.uniprot.org/uniprot/SECE_METJA SECE_METJA]] Essential subunit of the protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. [[http://www.uniprot.org/uniprot/SECY_METJA SECY_METJA]] The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
| |
| <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
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| __TOC__ | | __TOC__ |
| </SX> | | </SX> |
| [[Category: Atcc 43067]]
| |
| [[Category: Large Structures]] | | [[Category: Large Structures]] |
| [[Category: Methanococcus jannaschii]] | | [[Category: Methanocaldococcus jannaschii]] |
| [[Category: Akey, C W]] | | [[Category: Akey CW]] |
| [[Category: Gumbart, J C]] | | [[Category: Gumbart JC]] |
| [[Category: Li, W]] | | [[Category: Li W]] |
| [[Category: Ludtke, S J]] | | [[Category: Ludtke SJ]] |
| [[Category: Menetret, J F]] | | [[Category: Menetret JF]] |
| [[Category: Park, E]] | | [[Category: Park E]] |
| [[Category: Rapoport, T A]] | | [[Category: Rapoport TA]] |
| [[Category: Whynot, A]] | | [[Category: Whynot A]] |
| [[Category: Archaea]]
| |
| [[Category: Archaeal]]
| |
| [[Category: Co-translational translocation]]
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| [[Category: Large subunit]]
| |
| [[Category: Protein conducting channel]]
| |
| [[Category: Protein synthesis]]
| |
| [[Category: Ribosomal]]
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| [[Category: Ribosome-protein transport complex]]
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| [[Category: Rna]]
| |