4uuq: Difference between revisions

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<StructureSection load='4uuq' size='340' side='right'caption='[[4uuq]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
<StructureSection load='4uuq' size='340' side='right'caption='[[4uuq]], [[Resolution|resolution]] 2.36&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4uuq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UUQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4uuq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UUQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UUQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=64D:4-({[(4-CHLOROPHENYL)SULFONYL]AMINO}METHYL)PIPERIDINE-1-CARBOXYLIC+ACID'>64D</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=64D:4-({[(4-CHLOROPHENYL)SULFONYL]AMINO}METHYL)PIPERIDINE-1-CARBOXYLIC+ACID'>64D</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acylglycerol_lipase Acylglycerol lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.23 3.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uuq OCA], [https://pdbe.org/4uuq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uuq RCSB], [https://www.ebi.ac.uk/pdbsum/4uuq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uuq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uuq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uuq OCA], [http://pdbe.org/4uuq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uuq RCSB], [http://www.ebi.ac.uk/pdbsum/4uuq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uuq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MGLL_HUMAN MGLL_HUMAN]] Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.<ref>PMID:20079333</ref>
[https://www.uniprot.org/uniprot/MGLL_HUMAN MGLL_HUMAN] Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.<ref>PMID:20079333</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Lipase|Lipase]]
*[[Lipase 3D Structures|Lipase 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acylglycerol lipase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arlt, H]]
[[Category: Arlt H]]
[[Category: Auge, F]]
[[Category: Auge F]]
[[Category: Avenet, P]]
[[Category: Avenet P]]
[[Category: Beeske, S]]
[[Category: Beeske S]]
[[Category: Bergis, O E]]
[[Category: Bergis OE]]
[[Category: Bert, L]]
[[Category: Bert L]]
[[Category: Bertrand, T]]
[[Category: Bertrand T]]
[[Category: Brittain, S]]
[[Category: Brittain S]]
[[Category: Didier, M]]
[[Category: Didier M]]
[[Category: Escoubet, J]]
[[Category: Escoubet J]]
[[Category: Even, L]]
[[Category: Even L]]
[[Category: Francon, D]]
[[Category: Francon D]]
[[Category: George, P]]
[[Category: George P]]
[[Category: Griebel, G]]
[[Category: Griebel G]]
[[Category: He, T]]
[[Category: He T]]
[[Category: Houtman, J]]
[[Category: Houtman J]]
[[Category: Leroy, T]]
[[Category: Leroy T]]
[[Category: Lopez-Grancha, M]]
[[Category: Lopez-Grancha M]]
[[Category: Menet, V]]
[[Category: Menet V]]
[[Category: Michot, N]]
[[Category: Michot N]]
[[Category: Mikol, V]]
[[Category: Mikol V]]
[[Category: Pichat, P]]
[[Category: Pichat P]]
[[Category: Rak, A]]
[[Category: Rak A]]
[[Category: Redon, N]]
[[Category: Redon N]]
[[Category: Sun, F]]
[[Category: Sun F]]
[[Category: Tolstykh, T]]
[[Category: Tolstykh T]]
[[Category: Vallee, F]]
[[Category: Vallee F]]
[[Category: Wiederschain, D]]
[[Category: Wiederschain D]]
[[Category: Yu, Q]]
[[Category: Yu Q]]
[[Category: Zhang, B]]
[[Category: Zhang B]]
[[Category: Hydrolase]]

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