4uo3: Difference between revisions

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 <StructureSection load='4uo3' size='340' side='right'caption='[[4uo3]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4uo3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/equine/richmond/1/2007(h3n8)) Influenza a virus (a/equine/richmond/1/2007(h3n8))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UO3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UO3 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4uo3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/equine/Richmond/1/2007(H3N8)) Influenza A virus (A/equine/Richmond/1/2007(H3N8))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UO3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UO3 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unw|4unw]], [[4unx|4unx]], [[4uny|4uny]], [[4unz|4unz]], [[4uo0|4uo0]], [[4uo1|4uo1]], [[4uo2|4uo2]], [[4uo4|4uo4]], [[4uo5|4uo5]], [[4uo6|4uo6]], [[4uo7|4uo7]], [[4uo8|4uo8]], [[4uo9|4uo9]], [[4uoa|4uoa]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uo3 OCA], [https://pdbe.org/4uo3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uo3 RCSB], [https://www.ebi.ac.uk/pdbsum/4uo3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uo3 ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uo3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uo3 OCA], [http://pdbe.org/4uo3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uo3 RCSB], [http://www.ebi.ac.uk/pdbsum/4uo3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uo3 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/C3TUR9_9INFA C3TUR9_9INFA]] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity).[RuleBase:RU003324][SAAS:SAAS008980_004_327643]
+[https://www.uniprot.org/uniprot/C3TUR9_9INFA C3TUR9_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity).[RuleBase:RU003324][SAAS:SAAS008980_004_327643]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 ==See Also==
-*[[Hemagglutinin|Hemagglutinin]]
+*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
 == References ==
 <references/>
@@ Line 27: / Line 26: @@
 </StructureSection>
 [[Category: Large Structures]]
-[[Category: Collins, P J]]
+[[Category: Collins PJ]]
-[[Category: Gamblin, S J]]
+[[Category: Gamblin SJ]]
-[[Category: Haire, L F]]
+[[Category: Haire LF]]
-[[Category: Martin, S R]]
+[[Category: Martin SR]]
-[[Category: Ogrodowicz, R W]]
+[[Category: Ogrodowicz RW]]
-[[Category: Skehel, J J]]
+[[Category: Skehel JJ]]
-[[Category: Vachieri, S G]]
+[[Category: Vachieri SG]]
-[[Category: Walker, P A]]
+[[Category: Walker PA]]
-[[Category: Xiong, X]]
+[[Category: Xiong X]]
-[[Category: Viral protein]]