4tyl: Difference between revisions

<table><tr><td colspan='2'>[[4tyl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TYL FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=39O:5-AMINO-1,3,6-TRIMETHYL-1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE'>39O</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tyl OCA], [https://pdbe.org/4tyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tyl RCSB], [https://www.ebi.ac.uk/pdbsum/4tyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tyl ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ATAD2_HUMAN ATAD2_HUMAN] May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells.<ref>PMID:17998543</ref>  

[[Category: Homo sapiens]]

[[Category: Chauder BA]]

[[Category: Fesik SW]]

[[Category: Harner MJ]]

[[Category: Phan J]]