8ar2: Difference between revisions
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==Solution structure of TLR5 transmembrane and cytoplasmic juxtamembrane regions== | |||
<StructureSection load='8ar2' size='340' side='right'caption='[[8ar2]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ar2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AR2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AR2 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ar2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ar2 OCA], [https://pdbe.org/8ar2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ar2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ar2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ar2 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TLR5_HUMAN TLR5_HUMAN] Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.<ref>PMID:11323673</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arseniev AS]] | |||
[[Category: Goncharuk MV]] | |||
[[Category: Goncharuk SA]] | |||
[[Category: Kornilov FD]] | |||
[[Category: Mineev KS]] | |||
[[Category: Shabalkina AV]] | |||