4tn3: Difference between revisions
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<StructureSection load='4tn3' size='340' side='right'caption='[[4tn3]], [[Resolution|resolution]] 3.20Å' scene=''> | <StructureSection load='4tn3' size='340' side='right'caption='[[4tn3]], [[Resolution|resolution]] 3.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4tn3]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4tn3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TN3 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tn3 OCA], [https://pdbe.org/4tn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tn3 RCSB], [https://www.ebi.ac.uk/pdbsum/4tn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tn3 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/G9MAP5_MACMU G9MAP5_MACMU] [https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Escherichia virus T4]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Macaca mulatta]] | ||
[[Category: Goldstone DC]] | |||
[[Category: Goldstone | [[Category: Kirkpatrick JJ]] | ||
[[Category: Kirkpatrick | [[Category: Stoye JP]] | ||
[[Category: Stoye | [[Category: Taylor IA]] | ||
[[Category: Taylor | |||