2n7a: Difference between revisions
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==Solution structure of the human Siglec-8 lectin domain== | ==Solution structure of the human Siglec-8 lectin domain== | ||
<StructureSection load='2n7a' size='340' side='right'caption='[[2n7a | <StructureSection load='2n7a' size='340' side='right'caption='[[2n7a]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2n7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2n7a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N7A FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n7a OCA], [https://pdbe.org/2n7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n7a RCSB], [https://www.ebi.ac.uk/pdbsum/2n7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n7a ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n7a OCA], [https://pdbe.org/2n7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n7a RCSB], [https://www.ebi.ac.uk/pdbsum/2n7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n7a ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SIGL8_HUMAN SIGL8_HUMAN] Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Allain | [[Category: Allain FH-T]] | ||
[[Category: Ernst | [[Category: Ernst B]] | ||
[[Category: Proepster | [[Category: Proepster JM]] | ||
[[Category: Rabbani | [[Category: Rabbani S]] | ||
[[Category: Schubert | [[Category: Schubert M]] | ||
[[Category: Yang | [[Category: Yang F]] | ||