1k4t: Difference between revisions

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[[Image:1k4t.gif|left|200px]]
[[Image:1k4t.gif|left|200px]]


{{Structure
<!--
|PDB= 1k4t |SIZE=350|CAPTION= <scene name='initialview01'>1k4t</scene>, resolution 2.10&Aring;
The line below this paragraph, containing "STRUCTURE_1k4t", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene>, <scene name='pdbligand=TGP:5&#39;-THIO-2&#39;-DEOXY-GUANOSINE+PHOSPHONIC+ACID'>TGP</scene>, <scene name='pdbligand=TTC:(S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3&#39;,4&#39;&#58;6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE'>TTC</scene>, <scene name='pdbligand=TTG:2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC+ACID'>TTG</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1k4t| PDB=1k4t  | SCENE= }}  
|RELATEDENTRY=[[1a35|1A35]], [[1a31|1A31]], [[1a36|1A36]], [[1k4s|1K4S]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4t OCA], [http://www.ebi.ac.uk/pdbsum/1k4t PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1k4t RCSB]</span>
}}


'''HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX'''
'''HUMAN DNA TOPOISOMERASE I (70 KDA) IN COMPLEX WITH THE POISON TOPOTECAN AND COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX'''
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[[Category: Staker, B L.]]
[[Category: Staker, B L.]]
[[Category: Stewart, L J.]]
[[Category: Stewart, L J.]]
[[Category: complex (isomerase/dna)]]
[[Category: Dna]]
[[Category: dna]]
[[Category: Drug]]
[[Category: drug]]
[[Category: Poison]]
[[Category: poison]]
[[Category: Topoisomerase i]]
[[Category: topoisomerase i]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 22:18:25 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:43:27 2008''

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