2mo5: Difference between revisions
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==hIFABP-oleate complex== | ==hIFABP-oleate complex== | ||
<StructureSection load='2mo5' size='340' side='right'caption='[[2mo5 | <StructureSection load='2mo5' size='340' side='right'caption='[[2mo5]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2mo5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2mo5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MO5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MO5 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mo5 OCA], [https://pdbe.org/2mo5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mo5 RCSB], [https://www.ebi.ac.uk/pdbsum/2mo5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mo5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mo5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mo5 OCA], [https://pdbe.org/2mo5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mo5 RCSB], [https://www.ebi.ac.uk/pdbsum/2mo5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mo5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/FABPI_HUMAN FABPI_HUMAN] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Headey | [[Category: Headey S]] | ||
[[Category: Mohanty | [[Category: Mohanty B]] | ||
[[Category: Patil | [[Category: Patil R]] | ||
[[Category: Porter | [[Category: Porter C]] | ||
[[Category: Scanlon | [[Category: Scanlon M]] | ||
Revision as of 11:02, 8 March 2023
hIFABP-oleate complexhIFABP-oleate complex
Structural highlights
FunctionFABPI_HUMAN FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. See Also |
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