8br9: Difference between revisions

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'''Unreleased structure'''


The entry 8br9 is ON HOLD  until Paper Publication
==Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22==
 
<StructureSection load='8br9' size='340' side='right'caption='[[8br9]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
Authors: Pantelejevs, T., Hyvonen, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8br9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BR9 FirstGlance]. <br>
Description: Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=RF6:4,6-diethylpyrimidin-2-amine'>RF6</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8br9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8br9 OCA], [https://pdbe.org/8br9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8br9 RCSB], [https://www.ebi.ac.uk/pdbsum/8br9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8br9 ProSAT]</span></td></tr>
[[Category: Hyvonen, M]]
</table>
[[Category: Pantelejevs, T]]
== Function ==
[https://www.uniprot.org/uniprot/RADA_PYRFU RADA_PYRFU] Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus]]
[[Category: Hyvonen M]]
[[Category: Pantelejevs T]]

Revision as of 10:33, 8 March 2023

Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22Stapled peptide SP24 in complex with humanised RadA mutant HumRadA22

Structural highlights

8br9 is a 2 chain structure with sequence from Homo sapiens and Pyrococcus furiosus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RADA_PYRFU Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.

8br9, resolution 1.63Å

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