4ri4: Difference between revisions

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==Crystal structure of PTPN3 (PTPH1) Y676I mutant in complex with vanadate==
==Crystal structure of PTPN3 (PTPH1) Y676I mutant in complex with vanadate==
<StructureSection load='4ri4' size='340' side='right' caption='[[4ri4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='4ri4' size='340' side='right'caption='[[4ri4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ri4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RI4 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ri4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RI4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4rh5|4rh5]], [[4rh9|4rh9]], [[4rhg|4rhg]], [[4ri5|4ri5]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ri4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ri4 OCA], [https://pdbe.org/4ri4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ri4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ri4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ri4 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PTPH1, PTPN3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ri4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ri4 OCA], [http://pdbe.org/4ri4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ri4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ri4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ri4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PTN3_HUMAN PTN3_HUMAN]] May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.  
[https://www.uniprot.org/uniprot/PTN3_HUMAN PTN3_HUMAN] May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Large Structures]]
[[Category: Chen, K E]]
[[Category: Chen K-E]]
[[Category: Meng, T C]]
[[Category: Meng TC]]
[[Category: Wang, A H.J]]
[[Category: Wang AH-J]]
[[Category: Alpha beta]]
[[Category: Hydrolase]]

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