4r6r: Difference between revisions

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<StructureSection load='4r6r' size='340' side='right'caption='[[4r6r]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
<StructureSection load='4r6r' size='340' side='right'caption='[[4r6r]], [[Resolution|resolution]] 1.38&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4r6r]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R6R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R6R FirstGlance]. <br>
<table><tr><td colspan='2'>[[4r6r]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Artocarpus_integer Artocarpus integer]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R6R FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=147:1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE'>147</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=147:1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE'>147</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1jac|1jac]], [[1ugw|1ugw]], [[1ku8|1ku8]], [[1m26|1m26]], [[1uh0|1uh0]], [[1ugy|1ugy]], [[4r6n|4r6n]], [[4r6o|4r6o]], [[4r6p|4r6p]], [[4r6q|4r6q]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r6r OCA], [https://pdbe.org/4r6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r6r RCSB], [https://www.ebi.ac.uk/pdbsum/4r6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r6r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r6r OCA], [http://pdbe.org/4r6r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r6r RCSB], [http://www.ebi.ac.uk/pdbsum/4r6r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r6r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum. [[http://www.uniprot.org/uniprot/LECB3_ARTIN LECB3_ARTIN]] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.  
[https://www.uniprot.org/uniprot/LECA_ARTIN LECA_ARTIN] D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum.
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Artocarpus integer]]
[[Category: Artocarpus integer]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Abhinav, K V]]
[[Category: Abhinav KV]]
[[Category: Sharma, K]]
[[Category: Sharma K]]
[[Category: Surolia, A]]
[[Category: Surolia A]]
[[Category: Swaminathan, C P]]
[[Category: Swaminathan CP]]
[[Category: Vijayan, M]]
[[Category: Vijayan M]]
[[Category: Beta-prism i fold]]
[[Category: Galactose and sugar binding protein]]
[[Category: Galactose specific lectin]]
[[Category: Plant lectin]]
[[Category: Post translational proteolysis]]
[[Category: Sugar binding protein]]
[[Category: T-antigen binding protein]]

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