Trimethoprim: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
<StructureSection load='1dg5' size='350' side='right' caption='DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND TRIMETHOPRIM ([[1dg5]])' scene='95/952738/Cv/1'> | <StructureSection load='1dg5' size='350' side='right' caption='DIHYDROFOLATE REDUCTASE OF MYCOBACTERIUM TUBERCULOSIS COMPLEXED WITH NADPH AND TRIMETHOPRIM ([[1dg5]])' scene='95/952738/Cv/1'> | ||
<scene name='95/952738/Cv/5'>Trimethoprim</scene> is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections, and travelers' diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. Trimethoprim binds to [[dihydrofolate reductase]] and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). | <scene name='95/952738/Cv/5'>Trimethoprim</scene> is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections, and travelers' diarrhea. With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. Trimethoprim binds to [[dihydrofolate reductase]] and inhibits the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF). See also [https://en.wikipedia.org/wiki/Trimethoprim]. | ||
<scene name='95/952738/Cv/3'>Trimethoprim binding site</scene>. | <scene name='95/952738/Cv/3'>Trimethoprim binding site</scene>. | ||