Beta oxidation: Difference between revisions
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'''General mechanism''' | '''General mechanism''' | ||
Once the fatty acid is inside the mitochondrial matrix, beta-oxidation occurs by cleaving two carbons every cycle to form acetyl-CoA. The process consists of 4 steps. | Once the fatty acid is inside the mitochondrial matrix, beta-oxidation occurs by cleaving two carbons every cycle to form <scene name='43/430893/Cv/2'>acetyl-CoA</scene>. The process consists of 4 steps. | ||
1) A long-chain fatty acid is dehydrogenated to create a trans double bond between C2 and C3. This is catalyzed by [[acyl-CoA dehydrogenase]] to produce trans-delta 2-enoyl CoA. It uses FAD as an electron acceptor and it is reduced to FADH2. | 1) A long-chain fatty acid is dehydrogenated to create a trans double bond between C2 and C3. This is catalyzed by [[acyl-CoA dehydrogenase]] to produce trans-delta 2-enoyl CoA. It uses FAD as an electron acceptor and it is reduced to FADH2. | ||