4qkf: Difference between revisions

<table><tr><td colspan='2'>[[4qkf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QKF FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=OGA:N-OXALYLGLYCINE'>OGA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qkf OCA], [https://pdbe.org/4qkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qkf RCSB], [https://www.ebi.ac.uk/pdbsum/4qkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qkf ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/ALKB7_HUMAN ALKB7_HUMAN] Probable dioxygenase required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage. Does not display DNA demethylase activity. Involved in fatty acid metabolism.<ref>PMID:23666923</ref>  

*[[Dioxygenase 3D structures|Dioxygenase 3D structures]]

[[Category: Homo sapiens]]

[[Category: Chen Z]]

[[Category: Wang G]]