8b2a: Difference between revisions
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==Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative== | |||
<StructureSection load='8b2a' size='340' side='right'caption='[[8b2a]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8b2a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B2A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B2A FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PVI:(4R,5R)-3-amino-4,5-dihydroxy-cyclohexene-1-carboxylic+acid'>PVI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b2a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b2a OCA], [https://pdbe.org/8b2a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b2a RCSB], [https://www.ebi.ac.uk/pdbsum/8b2a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b2a ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AROD_STAAB AROD_STAAB] Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus]] | |||
[[Category: Gonzalez-Bello C]] | |||
[[Category: Hawkins AR]] | |||
[[Category: Lence E]] | |||
[[Category: Maneiro M]] | |||
[[Category: Otero JM]] | |||
[[Category: Rodriguez A]] | |||
[[Category: Thompson P]] | |||
[[Category: Van Raaij MJ]] | |||
Revision as of 13:26, 15 February 2023
Crystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivativeCrystal structure of type I dehydroquinase from Salmonella typhi inhibited by an epoxide derivative
Structural highlights
FunctionAROD_STAAB Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. |
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