7tx2: Difference between revisions

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-'''Unreleased structure'''
-The entry 7tx2 is ON HOLD  until Paper Publication
+==Crystal structure of human phenylethanolamine N-methyltransferase (PNMT) in complex with (2S)-2-amino-4-(((5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(4-(7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl)butyl)amino)butanoic acid==
+<StructureSection load='7tx2' size='340' side='right'caption='[[7tx2]], [[Resolution|resolution]] 2.43&Aring;' scene=''>
-Authors: Harijan, R.K., Mahmoodi, N., Minnow, Y.V.T., Bonanno, J.B., Almo, S.C., Schramm, V.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7tx2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TX2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TX2 FirstGlance]. <br>
-Description: Crystal structure of human phenylethanolamine N-methyltransferase (PNMT) in complex with (2S)-2-amino-4-(((5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)(4-(7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl)butyl)amino)butanoic acid
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KNX:5-([(3S)-3-amino-3-carboxypropyl]{4-[(4R)-7,8-dichloro-1,2,3,4-tetrahydroisoquinolin-4-yl]butyl}amino)-5-deoxyadenosine'>KNX</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tx2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tx2 OCA], [https://pdbe.org/7tx2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tx2 RCSB], [https://www.ebi.ac.uk/pdbsum/7tx2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tx2 ProSAT]</span></td></tr>
-[[Category: Almo, S.C]]
+</table>
-[[Category: Schramm, V.L]]
+== Function ==
-[[Category: Harijan, R.K]]
+[https://www.uniprot.org/uniprot/PNMT_HUMAN PNMT_HUMAN] Converts noradrenaline to adrenaline.
-[[Category: Minnow, Y.V.T]]
+__TOC__
-[[Category: Mahmoodi, N]]
+</StructureSection>
-[[Category: Bonanno, J.B]]
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Almo SC]]
+[[Category: Bonanno JB]]
+[[Category: Harijan RK]]
+[[Category: Mahmoodi N]]
+[[Category: Minnow YVT]]
+[[Category: Schramm VL]]